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[药物洗脱支架用于多支冠状动脉疾病:手术的重要堡垒之一被攻克了吗?]

[Drug-eluting stents in multivessel coronary artery disease: Was one of the important fortresses of surgery conquered?].

作者信息

Okmen Arda Sanli, Okmen Ertan

机构信息

Istanbul Memorial Hastanesi, Kardiyoloji Bölümü, Istanbul, Türkiye.

出版信息

Anadolu Kardiyol Derg. 2009 Aug;9(4):325-30.

PMID:19666436
Abstract

Since the drug eluting stents have provided better results concerning restenosis and repeat revascularization comparing to bare metal stents, percutaneous coronary interventions are performing increasingly in more complex stenoses. However, drug eluting stents did not show any advantage on prevention of myocardial infarction and survival. Currently there is no any completed controlled randomized study showing the superiority or equality of drug eluting stents over coronary bypass surgery by means of efficacy and safety. While the long-term results of drug eluting stents still unclear, everyday progressively more patients with multivessel disease are undergoing percutaneous coronary intervention with drug eluting stent implantation. The aim of this review is to discuss the efficacy and safety of drug eluting stents in patients with multivessel disease.

摘要

与裸金属支架相比,药物洗脱支架在再狭窄和重复血管重建方面取得了更好的效果,因此经皮冠状动脉介入治疗越来越多地应用于更复杂的狭窄病变。然而,药物洗脱支架在预防心肌梗死和提高生存率方面并未显示出任何优势。目前尚无任何完成的对照随机研究表明药物洗脱支架在疗效和安全性方面优于冠状动脉搭桥手术。虽然药物洗脱支架的长期效果仍不明确,但每天都有越来越多的多支血管病变患者接受植入药物洗脱支架的经皮冠状动脉介入治疗。本综述的目的是讨论药物洗脱支架在多支血管病变患者中的疗效和安全性。

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Anadolu Kardiyol Derg. 2009 Aug;9(4):325-30.
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