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高血压与糖尿病并存时:心肾保护策略

When hypertension and diabetes coexist: strategies for cardiorenal protection.

作者信息

Weber M A

机构信息

State University of New York Downstate College of Medicine, New York, USA.

出版信息

Postgrad Med. 2000 Oct;108(5 Suppl):12-8. doi: 10.3810/pgm.10.2000.suppl8.46.

DOI:10.3810/pgm.10.2000.suppl8.46
PMID:19667536
Abstract

Diabetes and hypertension frequently coexist, with effects potentially more detrimental than those of either condition alone. The combination increases the risk of both cardiovascular and renal morbidity and mortality. Antihypertensive drug therapy is of benefit to both nondiabetic and diabetic patients, but the greatest reduction in risk is seen in those with diabetes. Studies have shown the cardiorenal protective effects of therapy with angiotensin-converting enzyme inhibitors either alone or combined with calcium channel blockers. The data indicated the need for screening of hypertensive patients for diabetes and aggressive treatment to control hypertension.

摘要

糖尿病和高血压常常并存,其影响可能比单独任何一种疾病更具危害性。二者并存会增加心血管疾病和肾脏疾病的发病风险及死亡率。抗高血压药物治疗对非糖尿病患者和糖尿病患者均有益,但糖尿病患者的风险降低幅度最大。研究表明,单独使用血管紧张素转换酶抑制剂或与钙通道阻滞剂联合使用进行治疗具有心脏和肾脏保护作用。数据表明有必要对高血压患者进行糖尿病筛查并积极治疗以控制高血压。

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