Guthrie Robert M
The Ohio State University College of Medicine and Public Health, Columbus, OH 43212, USA.
Postgrad Med. 2003 Aug;114(2 Suppl):7-13. doi: 10.3810/pgm.08.2003.suppl28.151.
Over the last 2 decades, a large body of evidence has been collected that documents the value of identifying patients with lipid abnormalities and providing lipid-modifying therapy to reduce the risk of coronary heart disease (CHD) and related events. Yet the therapy that many such patients receive is not aggressive enough to be effective. With the aging of the US population and trends toward increasing obesity, diabetes, and impaired fasting glucose, primary care physicians are likely to be faced with growing numbers of patients at risk for CHD. It is imperative that these patients be given appropriate doses of cholesterol-lowering therapy and be encouraged to make therapeutic lifestyle changes.
在过去20年里，已经收集了大量证据，证明识别血脂异常患者并提供降脂治疗以降低冠心病（CHD）及相关事件风险的价值。然而，许多此类患者接受的治疗力度不足，难以奏效。随着美国人口老龄化以及肥胖、糖尿病和空腹血糖受损人数增加的趋势，初级保健医生可能会面临越来越多的冠心病高危患者。必须给这些患者给予适当剂量的降胆固醇治疗，并鼓励他们在治疗过程中改变生活方式。
