Cohen Jerome D, Egan Brent M
St Louis University Health Sciences Center, 3525 Caroline St, St Louis, MO 63104, USA.
Postgrad Med. 2003 Dec;114(6 Suppl Role):4-10. doi: 10.3810/pgm.12.2003.suppl33.198.
Activation of the sympathetic nervous system plays an important role in the development and maintenance of essential hypertension and the subsequent development of cardiac hypertrophy, heart failure, and sudden cardiac death. Current research suggests that pharmacologic treatment of hypertension should be aimed not only at lowering blood pressure, but also at inhibiting sympathetic drive.