Boktor Moheb, Mansi Ishak A, Troxclair Sean, Modi Kalgi
General Internal Medicine Section and Cardiology Section, Louisiana State University Health Science Center, Shreveport, LA 71130, USA.
South Med J. 2009 Sep;102(9):957-60. doi: 10.1097/SMJ.0b013e3181b08a30.
A woman presented with chest pain following emotional stress. Investigations showed acute ST-segment elevation, myocardial infarction, and elevated serum troponin. Emergency heart catheterization showed left anterior descending artery myocardial bridging, apical ballooning consistent with takotsubo cardiomyopathy (TTC), and decreased ejection fraction. Two days later, echocardiogram demonstrated near normalization of ventricular function.The etiology of TTC is not known but may include a stress-related surge of catecholamines or epicardial coronary spasm. Other case series reported an association of myocardial bridge and TTC. Catecholamines surge during stress might contribute to both diseases resulting in an apparent association; alternatively, a symptomatic myocardial bridge may be a contributing factor in worsening TTC.
一名女性在情绪应激后出现胸痛。检查显示急性ST段抬高、心肌梗死以及血清肌钙蛋白升高。紧急心脏导管检查显示左前降支心肌桥、符合应激性心肌病(TTC)的心尖部气球样变以及射血分数降低。两天后,超声心动图显示心室功能接近正常。TTC的病因尚不清楚,但可能包括与应激相关的儿茶酚胺激增或心外膜冠状动脉痉挛。其他病例系列报道了心肌桥与TTC之间的关联。应激期间儿茶酚胺激增可能导致这两种疾病,从而产生明显的关联;或者,有症状的心肌桥可能是TTC病情恶化的一个促成因素。