Allan B D, Short P, Crawford G J, Barrett G D, Constable I J
Lions Eye Institute, Perth, Australia.
Br J Ophthalmol. 1993 Nov;77(11):698-701. doi: 10.1136/bjo.77.11.698.
The optimum mode of treatment for symptomatic pterygia would combine efficacy (a low recurrence rate) with safety (freedom from sight threatening complications), and would not affect visual acuity adversely. The efficacy of pterygium excision with conjunctival autografting in a sun exposed population in which pterygia are prevalent has previously been questioned. A cross sectional review of 93 eyes of 85 patients was carried out by slit-lamp examination a minimum of 6 months (range 6-76 months) after pterygium excision and free conjunctival autografting. Case notes were reviewed to obtain details of complications and visual acuity changes related to surgery. Of six recurrences (6.5%) four of these were asymptomatic with minor recurrences. Two patterns of recurrence were identified: cross graft recurrence (three cases) and outflanking (three cases). Complications (wound dehiscence, three cases; Tenon's granuloma one case; conjunctival cyst, one case) were all corrected by minor surgical revision without sequelae. Unaided acuities were unchanged or improved 3 months after surgery in 86 cases, with a minor diminution (1 Snellen line) in seven cases. This study demonstrates a low recurrence rate for a safe technique in an area in which ongoing ultraviolet light exposure levels are high and pterygia are prevalent.
对于有症状的翼状胬肉,最佳治疗方式应兼具疗效(低复发率)与安全性(无威胁视力的并发症),且不会对视力产生不利影响。在翼状胬肉高发的阳光暴露人群中,翼状胬肉切除联合自体结膜移植术的疗效此前一直受到质疑。对85例患者的93只眼进行了横断面研究,在翼状胬肉切除及游离结膜自体移植术后至少6个月(6 - 76个月)进行裂隙灯检查。查阅病历以获取与手术相关的并发症及视力变化的详细信息。6例复发(6.5%)中,4例为无症状的轻度复发。确定了两种复发模式:交叉移植复发(3例)和包绕复发(3例)。并发症(伤口裂开,3例;Tenon肉芽肿1例;结膜囊肿1例)均通过小型手术修复得到纠正,无后遗症。86例患者术后3个月时,未矫正视力未变或改善,7例有轻微下降(1行Snellen视力表)。本研究表明,在紫外线持续暴露水平高且翼状胬肉高发的地区,该安全技术的复发率较低。