年龄相关性黄斑变性：当前的治疗方法
Age-related macular degeneration: current treatments.
作者信息
Hubschman Jean Pierre, Reddy Shantan, Schwartz Steven D
机构信息
Jules Stein Eye Institute, Department of Ophthalmology, University of California, David Geffen School of Medicine, Los Angeles, California, USA.
出版信息
Clin Ophthalmol. 2009;3:155-66. doi: 10.2147/opth.s2094. Epub 2009 Jun 2.
PURPOSE
Although important progress has been made in understanding age-related macular degeneration (AMD), management of the disease continues to be a challenge. AMD research has led to a widening of available treatment options and improved prognostic perspectives. This essay reviews these treatment options.
DESIGN
Interpretative essay.
METHODS
Literature review and interpretation.
RESULTS
Current treatments to preserve vision in patients with non-exudative AMD include antioxidant vitamins and mineral supplementations. Exudative AMD is currently most often treated monthly with anti-VEGF intravitreal injections. However, investigators are beginning to experiment with combination therapy and surgical approaches in an attempt to limit the number of treatment and reduce the financial burden on the health care system.
CONCLUSION
By better understanding the basis and pathogenesis of AMD, newer therapies will continue to be developed that target specific pathways in patients with AMD, with the hoped for outcome of better management of the disease and improved visual acuity.
目的
尽管在理解年龄相关性黄斑变性（AMD）方面已取得重要进展，但该疾病的管理仍然是一项挑战。AMD研究使得可用治疗选择不断增加，预后前景得到改善。本文综述了这些治疗选择。
设计
解释性论文。
方法
文献综述与解读。
结果
目前用于保护非渗出性AMD患者视力的治疗方法包括抗氧化维生素和矿物质补充剂。渗出性AMD目前最常通过每月一次的抗VEGF玻璃体内注射进行治疗。然而，研究人员开始尝试联合治疗和手术方法，以试图减少治疗次数并减轻医疗保健系统的经济负担。
结论
通过更好地理解AMD的基础和发病机制，将继续开发针对AMD患者特定途径的新疗法，以期更好地管理该疾病并提高视力。
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