Cimarolli Verena R, Casten Robin J, Rovner Barry W, Heyl Vera, Sörensen Silvia, Horowitz Amy
Research Institute on Aging, Jewish Home Lifecare, New York, NY, USA.
Department of Psychiatry and Human Behavior, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA, USA.
Clin Ophthalmol. 2015 Dec 30;10:55-63. doi: 10.2147/OPTH.S80489. eCollection 2016.
Age-related macular degeneration (AMD) - despite advances in prevention and medical treatment options - remains prevalent among older adults, often resulting in functional losses that negatively affect the mental health of older adults. In particular, the prevalence of both anxiety and depression in patients with AMD is high. Along with medical treatment options, low vision rehabilitation and AMD-specific behavioral and self-management programs have been developed and have demonstrated effectiveness in improving the mental health of AMD patients. This article reviews the prevalence of anxiety and depression in patients with advanced AMD, discusses potential mechanisms accounting for the development of depression and anxiety in AMD patients, presents the state-of the-art of available interventions for addressing anxiety and depression in AMD patients, and delineates recommendations for eye care professionals regarding how to screen for these two prevalent mental health problems and how to facilitate appropriate treatment for patients with AMD.
年龄相关性黄斑变性（AMD）——尽管在预防和治疗选择方面取得了进展——在老年人中仍然很普遍，常常导致功能丧失，对老年人的心理健康产生负面影响。特别是，AMD患者中焦虑和抑郁的患病率都很高。除了治疗选择外，低视力康复以及针对AMD的行为和自我管理项目已经得到开发，并已证明在改善AMD患者的心理健康方面有效。本文综述了晚期AMD患者中焦虑和抑郁的患病率，讨论了导致AMD患者发生抑郁和焦虑的潜在机制，介绍了针对AMD患者焦虑和抑郁的现有干预措施的现状，并就如何筛查这两种常见的心理健康问题以及如何促进AMD患者的适当治疗向眼科护理专业人员提出了建议。
