异戊烯基转移酶底物结合口袋的灵活性及其在类异戊二烯谱分析中的应用。
Prenyltransferase substrate binding pocket flexibility and its application in isoprenoid profiling.
作者信息
Xiao Youli, Machacek Miranda, Lee Kent, Kuzuyama Tomohisha, Liu Pinghua
机构信息
Department of Chemistry, Boston University, MA 02215, USA.
出版信息
Mol Biosyst. 2009 Sep;5(9):913-7. doi: 10.1039/b902370d. Epub 2009 Mar 26.
DOI:10.1039/b902370d
PMID:19668852
Abstract
This communication explores prenyltransferase substrate binding pocket flexibility to tag and enrich isoprenoids using affinity-based purification for metabolomic studies.
摘要
本通讯探讨了异戊二烯基转移酶底物结合口袋的灵活性，以便利用基于亲和力的纯化方法标记和富集类异戊二烯，用于代谢组学研究。
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