Paredes-Quijada Gerardo, Aranda-Espinoza Helim, Maldonado Amir
Posgrado en Polímeros y Materiales, Universidad de Sonora, 83000 Hermosillo, Sonora, Mexico.
J Biol Phys. 2006 Oct;32(2):177-81. doi: 10.1007/s10867-006-9007-y. Epub 2006 Apr 27.
We studied the shape of phospholipid vesicles prepared by hydration of a mixture of phosphatidylcholine (SOPC) and phosphatidylserine (SOPS) in different proportions. The aim of the work is to obtain some insight into the influence of the chemical composition of a biomembrane on its shape. The optical microscopy results show that the shape of the vesicles depend on the SOPC:SOPS composition. For low SOPS contents, coiled cylindrical vesicles are observed. The results suggest that specific compositions of the SOPC:SOPS vesicles produce some spontaneous curvature on the membrane and then a coiling instability.
我们研究了通过水化不同比例的磷脂酰胆碱（SOPC）和磷脂酰丝氨酸（SOPS）混合物制备的磷脂囊泡的形状。这项工作的目的是深入了解生物膜的化学成分对其形状的影响。光学显微镜结果表明，囊泡的形状取决于SOPC:SOPS的组成。对于低SOPS含量，观察到盘绕的圆柱形囊泡。结果表明，SOPC:SOPS囊泡的特定组成会在膜上产生一些自发曲率，进而导致盘绕不稳定性。
