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混合磷脂囊泡的形状。

Shapes of mixed phospholipid vesicles.

作者信息

Paredes-Quijada Gerardo, Aranda-Espinoza Helim, Maldonado Amir

机构信息

Posgrado en Polímeros y Materiales, Universidad de Sonora, 83000 Hermosillo, Sonora, Mexico.

出版信息

J Biol Phys. 2006 Oct;32(2):177-81. doi: 10.1007/s10867-006-9007-y. Epub 2006 Apr 27.

Abstract

We studied the shape of phospholipid vesicles prepared by hydration of a mixture of phosphatidylcholine (SOPC) and phosphatidylserine (SOPS) in different proportions. The aim of the work is to obtain some insight into the influence of the chemical composition of a biomembrane on its shape. The optical microscopy results show that the shape of the vesicles depend on the SOPC:SOPS composition. For low SOPS contents, coiled cylindrical vesicles are observed. The results suggest that specific compositions of the SOPC:SOPS vesicles produce some spontaneous curvature on the membrane and then a coiling instability.

摘要

我们研究了通过水化不同比例的磷脂酰胆碱(SOPC)和磷脂酰丝氨酸(SOPS)混合物制备的磷脂囊泡的形状。这项工作的目的是深入了解生物膜的化学成分对其形状的影响。光学显微镜结果表明,囊泡的形状取决于SOPC:SOPS的组成。对于低SOPS含量,观察到盘绕的圆柱形囊泡。结果表明,SOPC:SOPS囊泡的特定组成会在膜上产生一些自发曲率,进而导致盘绕不稳定性。

相似文献

1
Shapes of mixed phospholipid vesicles.混合磷脂囊泡的形状。
J Biol Phys. 2006 Oct;32(2):177-81. doi: 10.1007/s10867-006-9007-y. Epub 2006 Apr 27.
2
Shapes and coiling of mixed phospholipid vesicles.混合磷脂囊泡的形状与盘绕
Lipids. 2009 Mar;44(3):283-9. doi: 10.1007/s11745-009-3280-z. Epub 2009 Jan 27.

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