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女性阻塞性睡眠呼吸暂停与性功能障碍。

Sexual dysfunction in women with obstructive sleep apnea.

机构信息

Division of Pulmonary, Critical Care and Sleep Medicine, Baylor College of Medicine, Houston, TX, 77025, USA.

出版信息

Sleep Breath. 2010 Feb;14(1):59-62. doi: 10.1007/s11325-009-0280-4. Epub 2009 Aug 11.

Abstract

BACKGROUND

Female sexual dysfunction is vastly under-recognized but has been previously described in chronic disease states. Sexual dysfunction in male patients with obstructive sleep apnea (OSA) is well described, but not in females.

OBJECTIVE

The objective of this study was to assess the prevalence of sexual dysfunction in women with OSA.

METHODS

We studied 21 consecutive pre-menopausal women with OSA, referred to our sleep lab, and who had a positive study for sleep apnea (respiratory disturbance index (RDI) > 5), and 11 healthy pre-menopausal women were included as the control group. Subjects were administered the Female Sexual Function Index (FSFI) questionnaire and a mood scale-Profile of Mood States.

RESULTS

Of the study group, 11 women (52.4%) had FSFI scores in the poor range (<23) as compared to the control group, in which none of the women (0%) had FSFI scores in the poor range (<23). Negative mood domain scores were not different in patients with poor FSFI compared to patients with normal FSFI scores. There was no correlation between obesity, severity of sleep apnea, or mood disorders on overall scores of sexual dysfunction. Among individual domains, there was a correlation between RDI and arousal scores.

CONCLUSION

In our study, we have found that prevalence of sexual dysfunction is high among women with OSA. Physicians should routinely screen and evaluate women with OSA for sexual dysfunction.

摘要

背景

女性性功能障碍的认识度严重不足,但在慢性疾病状态下已有相关描述。男性阻塞性睡眠呼吸暂停(OSA)患者的性功能障碍已有相关描述,但女性患者则不然。

目的

本研究旨在评估 OSA 女性患者性功能障碍的患病率。

方法

我们研究了 21 名连续的绝经前 OSA 女性患者,她们均被转诊至我们的睡眠实验室,且睡眠呼吸暂停检测结果呈阳性(呼吸紊乱指数(RDI)>5),同时纳入了 11 名健康的绝经前女性作为对照组。所有受试者均完成了女性性功能指数(FSFI)问卷和情绪量表-心境状态问卷的评估。

结果

在研究组中,11 名女性(52.4%)的 FSFI 评分处于较差范围(<23),而对照组中无一女性(0%)的 FSFI 评分处于较差范围(<23)。与 FSFI 评分正常的患者相比,FSFI 评分较差的患者负面情绪域评分并无差异。肥胖、睡眠呼吸暂停严重程度或整体性功能障碍的情绪障碍评分与性功能障碍的严重程度之间均无相关性。在各单项指标中,RDI 与唤起评分之间存在相关性。

结论

在本研究中,我们发现 OSA 女性性功能障碍的患病率较高。医生应常规筛查和评估 OSA 女性患者的性功能障碍。

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