Yilmaz Zahide, Sirinocak Pinar Bekdik, Voyvoda Bekir, Ozcan Levent
Derince Training and Research Hospital, Department of Neurology, Kocaeli, Turkey.
Derince Training and Research Hospital, Department of Urology, Kocaeli, Turkey.
Urol J. 2017 Nov 4;14(6):5051-5056. doi: 10.22037/uj.v14i6.3891.
Sexual functions in the males with obstructive sleep apnea syndrome (OSAS) have been well investigated in the literature; however sexual functions in the premenopausal women with OSAS have been studied to a lesser extent.
The study included 22 premenopausal women diagnosed as OSAS by the polysomnographic (PSG) evaluation. The control group included 13 premenopausal women suspected of sleep-relatedrespiratory disorder, but whose PSG tests were determined to be normal. Both groups were administered Epworth Sleep Scale (ESS), Beck Depression Scale (BDS), and Female Sexual Function Index (FSFI) questionnaire forms. Relations between disease parameters, and the total FSFI score, and scores of the six FSFI parameter were analyzed.
The total FSFI score in the cases with OSAS, was determined to be significantly lower than that of the control subjects (P = .031). Scores of the desire, arousal, and orgasm were determined to be significantly lower inthe patient group, compared to control group (P = .034; P = .048; P = .039). The total FSFI scores, and scores of the desire, arousal, lubrication, orgasm, satisfaction and pain subscales in the cases did not correlate significantly with the apnea-hypopnea index (AHI), Non-Rapid Eye Movement 1 (NREM1)%, NREM2%, NREM3%, REM%, the time spent with saturation O2< 90%, minimum oxygen saturation (%), ESS scores, and BDS scores (all P > .05).
Women with OSAS experience sexual dysfunction when compared with normal population. Clinical evaluation has to include also the evaluation of sexual life in women.
阻塞性睡眠呼吸暂停综合征（OSAS）男性患者的性功能在文献中已有充分研究；然而，绝经前OSAS女性患者的性功能研究较少。
本研究纳入22例经多导睡眠图（PSG）评估诊断为OSAS的绝经前女性。对照组包括13例疑似睡眠相关呼吸障碍但PSG检查确定正常的绝经前女性。两组均接受爱泼华嗜睡量表（ESS）、贝克抑郁量表（BDS）和女性性功能指数（FSFI）问卷。分析疾病参数与FSFI总分及六个FSFI参数得分之间的关系。
OSAS患者的FSFI总分显著低于对照组（P = 0.031）。与对照组相比，患者组的性欲、性唤起和性高潮得分显著降低（P = 0.034；P = 0.048；P = 0.039）。患者的FSFI总分以及性欲、性唤起、润滑、性高潮、满意度和疼痛分量表得分与呼吸暂停低通气指数（AHI）、非快速眼动睡眠1期（NREM1）%、NREM2%、NREM3%、快速眼动睡眠（REM）%、血氧饱和度<90%的时间、最低血氧饱和度（%）、ESS得分和BDS得分均无显著相关性（所有P>0.05）。
与正常人群相比，OSAS女性存在性功能障碍。临床评估还必须包括对女性性生活的评估。
