铅缺乏大鼠红细胞膜中钠钾ATP酶和钙镁ATP酶的活性
Activity of Na-K-ATPase and Ca-Mg-ATPase in red blood cell membranes of lead-depleted rats.
作者信息
Eder K, Reichlmayr-Lais A M, Kirchgessner M
机构信息
Institut für Ernährungsphysiologie, Technische Universität München-Weihenstephan, Freising, Fed. Rep. of Germany.
出版信息
J Trace Elem Electrolytes Health Dis. 1990 Mar;4(1):21-4.
Na-K-ATPase and Ca-Mg-ATPase activity of erythrocyte membranes from lead-depleted rats were determined. In P0 generation there was no difference in activity of Na-K-ATPase and Ca-Mg-ATPase between control and depletion rats. In contrast to this, in F1 generation lead-depleted rats showed reduced activity of both enzymes. Possibly, these changes of Na-K-ATPase and Ca-Mg-ATPase activity cause the reduction of the mean corpuscular cell volume (MCV) observed in former lead depletion studies.
测定了低铅大鼠红细胞膜的钠钾ATP酶和钙镁ATP酶活性。在P0代，对照大鼠和低铅大鼠的钠钾ATP酶和钙镁ATP酶活性没有差异。与此相反，在F1代，低铅大鼠的这两种酶活性均降低。钠钾ATP酶和钙镁ATP酶活性的这些变化可能导致了先前低铅研究中观察到的平均红细胞体积（MCV）的降低。
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