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[多种哺乳动物中无核红细胞膜的转运ATP酶活性及蛋白质-脂质组成特征]

[The activity of transport ATPases and the characteristics of the protein-lipid composition of the membranes of anuclear erythrocytes in a number of mammals].

作者信息

Matskevich Iu A, Kazennov A M, Maslova M N

出版信息

Zh Evol Biokhim Fiziol. 1994 Jul-Aug;30(4):497-504.

PMID:7863741
Abstract

The activity of Na,K-ATPase and Ca-ATPase of the intact erythrocytes and their membrane preparations and also fatty acid, phospholipid and protein content of erythrocyte membrane of guinea pig, mouse, rabbit and hamster have been examined. The activity of Na,K- and Ca-ATPase in intact erythrocytes varies significantly among different species while the level of activity of these enzymes in their membrane preparations differs slightly. Together with the results of investigations of chemical composition of the erythrocyte membrane of these species which show the principal homogeneity of their fatty acid, phospholipid and protein composition, these data indicate the existence of the system of intracellular modulators, that maintain the activity of these enzymes on the species specific level.

摘要

已对豚鼠、小鼠、兔子和仓鼠完整红细胞及其膜制剂的钠钾 - 三磷酸腺苷酶(Na,K - ATPase)和钙 - 三磷酸腺苷酶(Ca - ATPase)活性,以及红细胞膜的脂肪酸、磷脂和蛋白质含量进行了检测。完整红细胞中Na,K - ATPase和Ca - ATPase的活性在不同物种间差异显著,而这些酶在其膜制剂中的活性水平差异较小。连同对这些物种红细胞膜化学成分的研究结果表明它们的脂肪酸、磷脂和蛋白质组成基本同质,这些数据表明存在细胞内调节剂系统,该系统将这些酶的活性维持在物种特异性水平。

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