Ai Wei, Tong Busheng, Liu Yehai, Duan Maoli
Department of Otolaryngology-Head and Neck Surgery, the First Affiliated Hospital of Anhui Medical University, Hefei, 230032, China.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2009 Apr;23(7):307-10.
To analyze the clinical characteristics and treatment of bilateral and unilateral sudden sensorineural hearing loss (SSHL) and figure out the differences between bi-and unilateral sudden sensorineural hearing loss, and further improve the diagnosis and treatment of SSHL.
The retrospective study was based on 334 patients with SSHL (315 with uni-SSHL versus 18 with bi-SSHL) and all of the patients were in-patients.
The incidence of bi-SSHL was 5.4% of patients with SSHL. There was no significant difference on the clinical features such as age, gender, interval from onset of symptoms to seeing doctors and associated symptoms between bi-and unilateral SSHL. 27.8% of the patients with bi-SSHL had preexisting diabetes mellitus, which was significantly higher than the rate of the uni-SSHL (9.8%, P<0.05). Hearing loss was more profound in the uni-SSHL ones, however, the hearing improvements were better than their counterparts. The overall effective rate of the two groups was 58.4% and 13.9% respectively. Earlier diagnosis and treatment with steroids would have a good prognosis.
Unilateral SSHL is more common than bilateral SSHL. Bilateral SSHL occurs more common with preexisting diabetes mellitus and has worse prognosis compared to unilateral SSHL. The earlier steroid treatment the better prognosis.
分析双侧和单侧突发性感音神经性听力损失（SSHL）的临床特征及治疗情况，明确双侧与单侧突发性感音神经性听力损失之间的差异，进一步提高SSHL的诊治水平。
本回顾性研究基于334例SSHL患者（315例单侧SSHL，18例双侧SSHL），所有患者均为住院患者。
双侧SSHL的发病率占SSHL患者的5.4%。双侧与单侧SSHL在年龄、性别、症状出现至就诊间隔时间及相关症状等临床特征方面无显著差异。27.8%的双侧SSHL患者患有糖尿病，显著高于单侧SSHL患者的比例（9.8%，P<0.05）。单侧SSHL患者听力损失更严重，然而其听力改善情况优于双侧SSHL患者。两组的总体有效率分别为58.4%和13.9%。早期使用类固醇进行诊断和治疗预后良好。
单侧SSHL比双侧SSHL更常见。双侧SSHL在糖尿病患者中更常见，与单侧SSHL相比预后更差。类固醇治疗越早，预后越好。
