Muzzi D A, Black S, Losasso T J, Cucchiara R F
Department of Anesthesiology, Mayo Clinic, Rochester, Minnesota 55905.
Anesth Analg. 1990 Jan;70(1):68-71.
The postoperative course of patients emerging from general anesthesia after intracranial surgery is frequently complicated by hypertension. This study examined the comparative efficacy of esmolol and labetalol in treating increases in blood pressure during emergence and recovery from anesthesia after intracranial surgery. Both esmolol and labetalol were equally effective in controlling systolic blood pressure on emergence and in the recovery room in patients undergoing intracranial surgery. However, decreases in heart rate were significantly more frequent in the immediate postoperative period in patients given labetalol. An increase in blood pressure after intracranial surgery appears to be a transitory phenomenon adequately treated with a short-acting antihypertensive agent such as esmolol.
颅内手术后从全身麻醉中苏醒的患者术后过程常并发高血压。本研究考察了艾司洛尔和拉贝洛尔在治疗颅内手术后麻醉苏醒和恢复过程中血压升高方面的比较疗效。在接受颅内手术的患者中，艾司洛尔和拉贝洛尔在控制苏醒时和恢复室中的收缩压方面同样有效。然而，给予拉贝洛尔的患者在术后即刻心率下降明显更频繁。颅内手术后的血压升高似乎是一种短暂现象，用艾司洛尔等短效抗高血压药物可得到充分治疗。
