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危重症患者白色念珠菌芽管抗体的动力学模式:对死亡率的影响

Kinetic patterns of Candida albicans germ tube antibody in critically ill patients: influence on mortality.

作者信息

Zaragoza Rafael, Pemán Javier, Quindós Guillermo, Iruretagoyena Jose R, Cuétara María S, Ramírez Paula, Gómez Maria D, Camarena Juan J, Viudes Angel, Pontón José

机构信息

Intensive Care Unit and Department of Microbiology, Valencia, Spain.

出版信息

Clin Vaccine Immunol. 2009 Oct;16(10):1527-8. doi: 10.1128/CVI.00183-09. Epub 2009 Aug 12.

Abstract

The influence of kinetic patterns of Candida albicans germ tube antibodies (CAGTA) on mortality was analyzed in six intensive care units. Statistically significant lower mortality rates were found in patients with patterns of increasing CAGTA titers who had been treated with antifungal agents. Thus, antifungal treatment should be considered when CAGTA titers are increasing in critically ill patients.

摘要

在六个重症监护病房分析了白色念珠菌芽管抗体(CAGTA)动力学模式对死亡率的影响。在接受抗真菌药物治疗且CAGTA滴度呈上升模式的患者中,发现死亡率显著降低。因此,当重症患者的CAGTA滴度升高时,应考虑进行抗真菌治疗。

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