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从未接受过抗精神病药物治疗的精神分裂症患者的终生预后及不自主运动。爱尔兰的4例罕见病例。

The lifetime outcome and involuntary movements of schizophrenia never treated with neuroleptic drugs. Four rare cases in Ireland.

作者信息

Waddington J L, Youssef H A

机构信息

Royal College of Surgeons in Ireland, Dublin.

出版信息

Br J Psychiatry. 1990 Jan;156:106-8. doi: 10.1192/bjp.156.1.106.

DOI:10.1192/bjp.156.1.106
PMID:1967543
Abstract

Four elderly schizophrenic patients who had never been treated with neuroleptics, and a fifth patient who had received only the briefest exposure to such drugs, had retained their distinct clinical characteristics. Involuntary orofacial movements and cognitive dysfunction were found more uniformly than any particular pattern of symptoms.

摘要

四名从未接受过抗精神病药物治疗的老年精神分裂症患者,以及第五名仅短暂接触过此类药物的患者,都保留了各自独特的临床特征。与任何特定症状模式相比,不自主口面部运动和认知功能障碍更为普遍。

相似文献

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引用本文的文献

1
Neurological signs and involuntary movements in schizophrenia: intrinsic to and informative on systems pathobiology.精神分裂症中的神经学体征与不自主运动:系统病理生物学的内在特征及信息来源
Schizophr Bull. 2009 Mar;35(2):415-24. doi: 10.1093/schbul/sbn126. Epub 2008 Sep 12.
2
Behavioral and antioxidant activity of a tosylbenz[g]indolamine derivative. A proposed better profile for a potential antipsychotic agent.一种甲苯磺酰苯并[g]吲哚胺衍生物的行为和抗氧化活性。一种潜在抗精神病药物的更好特性建议。
Ann Gen Hosp Psychiatry. 2004 Jan 7;3(1):1. doi: 10.1186/1475-2832-3-1.
3
Motor deficits and schizophrenia: the evidence from neuroleptic-naïve patients and populations at risk.
运动功能缺损与精神分裂症:来自未服用抗精神病药物患者及高危人群的证据
J Psychiatry Neurosci. 1999 Sep;24(4):304-14.
4
Movements in never-medicated schizophrenics: a preliminary study.未接受药物治疗的精神分裂症患者的运动:一项初步研究。
Psychopharmacology (Berl). 1996 Jan;123(2):206-10. doi: 10.1007/BF02246179.
5
Spontaneous orofacial movements induced in rodents by very long-term neuroleptic drug administration: phenomenology, pathophysiology and putative relationship to tardive dyskinesia.长期给予抗精神病药物诱导啮齿动物出现的自发性口面部运动:现象学、病理生理学及与迟发性运动障碍的假定关系
Psychopharmacology (Berl). 1990;101(4):431-47. doi: 10.1007/BF02244220.