White Brett
University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA.
Am Fam Physician. 2009 Aug 15;80(4):345-50.
Fatty acids can be divided into four general categories: saturated, monounsaturated, polyunsaturated, and trans fats. Saturated fatty acids and trans fats are associated with an increased risk of coronary heart disease. Monounsaturated fatty acids and polyunsaturated fatty acids are associated with a decreased risk of coronary heart disease, although these associations are not uniformly supported in the literature. Omega-3 fatty acids, which are a type of polyunsaturated fatty acid, have been studied as potential therapy for a variety of medical conditions because of their suspected anti-inflammatory properties. Omega-3 fatty acids have also been shown to provide some benefit to patients with cystic fibrosis, and may have a protective effect against dementia. Physicians should counsel patients about the importance of avoiding hydrogenated oils and foods containing trans fats because of their association with coronary heart disease in observational studies.
饱和脂肪酸、单不饱和脂肪酸、多不饱和脂肪酸和反式脂肪。饱和脂肪酸和反式脂肪与冠心病风险增加有关。单不饱和脂肪酸和多不饱和脂肪酸与冠心病风险降低有关,尽管这些关联在文献中并非得到一致支持。ω-3脂肪酸是一种多不饱和脂肪酸,因其具有抗炎特性而被研究作为多种医疗状况的潜在治疗方法。ω-3脂肪酸还被证明对囊性纤维化患者有一定益处,并且可能对痴呆症有保护作用。由于观察性研究表明氢化油和含反式脂肪的食物与冠心病有关,医生应建议患者了解避免食用这些食物的重要性。