Department of Obstetrics and Gynecology, University of Auckland, New Zealand.
J Reprod Immunol. 2009 Oct;82(1):66-73. doi: 10.1016/j.jri.2009.04.011. Epub 2009 Aug 12.
The aim of this study was to determine if women with preeclampsia or delivering small for gestational age (SGA) babies are more likely to have a short duration of sexual relationship compared with those who have uncomplicated pregnancies. In a prospective cohort study, 2507 nulliparous women with singleton pregnancies were interviewed at 15+/-1 weeks gestation about the duration of their sexual relationship with the biological father. Short duration of sexual relationship (< or =6 months, < or =3 months, or first intercourse) was compared between women with preeclampsia (N=131) or SGA babies (N=263) and those with uncomplicated pregnancies (N=1462). Short duration of sexual relationship was more common in women with preeclampsia compared with uncomplicated pregnancies (< or =6 months 14.5% versus 6.9%, adjusted odds ratio [adjOR] 1.88, 95% CI 1.05-3.36; < or =3 months 6.9% versus 2.5%, adjOR 2.32, 95% CI 1.03-5.25; first intercourse 1.5% versus 0.5%, adjOR 5.75, 95% CI 1.13-29.3). Although the total number of semen exposures was lower in SGA, SGA was not associated with a shorter duration of sexual relationship. On post hoc analysis, the subgroup of SGA with abnormal uterine artery Doppler at 20 weeks (N=58) were more likely to have had a short sexual relationship compared with controls (< or =6 months adjOR 2.33, 95% CI 1.09-4.98; < or =3 months adjOR 3.22, 95% CI 1.18-8.79; first intercourse adjOR 8.02, 95% CI 1.58-40.7). We conclude that compared to uncomplicated pregnancies, short duration of sexual relationship is more common in women who develop preeclampsia and women with abnormal uterine artery Doppler waveforms who deliver an SGA baby.
本研究旨在确定与无并发症妊娠相比，患有先兆子痫或分娩小于胎龄儿（SGA）的女性是否更有可能出现性关系持续时间较短的情况。在一项前瞻性队列研究中，对 2507 名初产妇在 15+/-1 周妊娠时进行了采访，询问了她们与生物学父亲的性关系持续时间。将患有先兆子痫（N=131）或 SGA 婴儿（N=263）的女性与无并发症妊娠（N=1462）的女性进行比较，观察其性关系持续时间较短的情况（<或=6 个月、<或=3 个月或初次性交）。与无并发症妊娠相比，患有先兆子痫的女性更有可能出现性关系持续时间较短的情况（<或=6 个月 14.5%比 6.9%，调整后的优势比[adjOR]1.88，95%置信区间[CI]1.05-3.36；<或=3 个月 6.9%比 2.5%，adjOR 2.32，95%CI 1.03-5.25；初次性交 1.5%比 0.5%，adjOR 5.75，95%CI 1.13-29.3）。尽管 SGA 的精液暴露总数较低，但 SGA 与性关系持续时间较短无关。在事后分析中，20 周时子宫动脉多普勒异常的 SGA 亚组（N=58）与对照组相比，更有可能出现性关系持续时间较短的情况（<或=6 个月 adjOR 2.33，95%CI 1.09-4.98；<或=3 个月 adjOR 3.22，95%CI 1.18-8.79；初次性交 adjOR 8.02，95%CI 1.58-40.7）。我们的结论是，与无并发症妊娠相比，患有先兆子痫和子宫动脉多普勒波形异常的女性中，出现性关系持续时间较短的情况更为常见，且她们分娩的婴儿为 SGA。
