Adelaide Medical School, University of Adelaide, South Australia, Australia; Robinson Research Institute, University of Adelaide, Australia.
Department of Obstetrics and Gynaecology, The University of Auckland, New Zealand.
J Reprod Immunol. 2018 Aug;128:16-22. doi: 10.1016/j.jri.2018.05.007. Epub 2018 May 18.
This study aims to determine if a short duration of sexual relationship is more common among women who experience adverse pregnancy outcomes including gestational hypertension (GHT), preeclampsia, small for gestational age (SGA) pregnancies and spontaneous preterm birth (sPTB) with or without abnormal uterine artery Doppler compared to women who have uncomplicated pregnancies. 5591 nulliparous women from the Screening for Pregnancy Endpoints (SCOPE) study were included. The risk for pregnancy complications for women who had a duration of sexual relationship of ≤3 months, 4-6 months, 7-9 months, 10-12 months was compared with women who had a duration of sexual relationship of >12 months. Uterine artery Doppler was performed at 20 ± 1 weeks' gestation. A short duration of sexual relationship (≤3 months) was more common among women with SGA in the presence of abnormal uterine artery Doppler [9.8% vs 3.0%, aOR (95% CI) 3.4 (1.6-7.08] compared to women who had uncomplicated pregnancies. A short duration of sexual relationship (≤3 months) was also more common among women who had abnormal uterine artery Doppler compared to those with normal uterine artery Doppler [6.1% vs 3.1%, aOR (95% CI) = 2.1 (1.4-3.2)]. A short duration of sexual relationship was not associated with preeclampsia after adjusting for confounders. A short duration of sexual relationship is more common among women who deliver SGA infants with features of placental insufficiency as indicated by abnormal uterine artery Doppler.
本研究旨在确定与无复杂妊娠的女性相比，经历不良妊娠结局（包括妊娠期高血压疾病（GHT）、子痫前期、胎儿生长受限（SGA）和自发性早产（sPTB）以及伴有或不伴有子宫动脉多普勒异常）的女性中，性伴侣关系持续时间较短的情况是否更为常见。共纳入了来自 Screening for Pregnancy Endpoints（SCOPE）研究的 5591 名初产妇。比较了性伴侣关系持续时间≤3 个月、4-6 个月、7-9 个月、10-12 个月的女性与性伴侣关系持续时间>12 个月的女性发生妊娠并发症的风险。在 20±1 孕周时进行子宫动脉多普勒检查。与无复杂妊娠的女性相比，存在子宫动脉多普勒异常的 SGA 孕妇中，性伴侣关系持续时间较短（≤3 个月）的情况更为常见[9.8% vs 3.0%，优势比（95%置信区间）3.4（1.6-7.08]。与子宫动脉多普勒正常的女性相比，子宫动脉多普勒异常的女性中，性伴侣关系持续时间较短（≤3 个月）的情况也更为常见[6.1% vs 3.1%，优势比（95%置信区间）=2.1（1.4-3.2）]。在调整混杂因素后，性伴侣关系持续时间较短与子痫前期无关。性伴侣关系持续时间较短与胎盘功能不全的特征有关，表现为子宫动脉多普勒异常，与 SGA 婴儿的分娩有关。
