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肺复张策略——临床医生指南

Lung recruitment--a guide for clinicians.

机构信息

The University of Queensland, School of Nursing and Midwifery, Herston, Australia.

出版信息

Aust Crit Care. 2009 Nov;22(4):155-62. doi: 10.1016/j.aucc.2009.06.004. Epub 2009 Aug 12.

DOI:10.1016/j.aucc.2009.06.004
PMID:19679490
Abstract

Recruitment manoeuvres play an important role in minimising ventilator associated lung injury (VALI) particularly when lung protective ventilation strategies are employed and as such clinicians should consider their application. This paper provides evidence-based recommendations for clinical practice with regard to alveolar recruitment. It includes recommendations for timing of recruitment, strategies of recruitment and methods of measuring the efficacy of recruitment manoeuvres and contributes to knowledge about the risks associated with recruitment manoeuvres. There are a range of methods for recruiting alveoli, most notably by manipulating positive end expiratory pressure (PEEP) and peak inspiratory pressure (PIP) with consensus as to the most effective not yet determined. A number of studies have demonstrated that improvement in oxygenation is rarely sustained following a recruitment manoeuvre and it is questionable whether improved oxygenation should be the clinician's goal. Transient haemodynamic compromise has been noted in a number of studies with a few studies reporting persistent, harmful sequelae to recruitment manoeuvres. No studies have been located that assess the impact of recruitment manoeuvres on length of ventilation, length of stay, morbidity or mortality. Recruitment manoeuvres restore end expiratory lung volume by overcoming threshold opening pressures and are most effective when applied after circuit disconnection and airway suction. Whether this ultimately improves outcomes in adult or paediatric populations is unknown.

摘要

募集手法在尽量减少呼吸机相关性肺损伤(VALI)方面起着重要作用,特别是在采用肺保护性通气策略时,因此临床医生应考虑应用这些手法。本文针对肺泡募集提供了基于证据的临床实践建议。它包括关于募集时机、募集策略以及评估募集手法效果的方法的建议,并有助于了解募集手法相关的风险。有多种募集肺泡的方法,最显著的是通过操纵呼气末正压(PEEP)和吸气峰压(PIP),但尚未确定哪种方法最有效。多项研究表明,在进行募集手法后,氧合改善很少能持续,改善氧合是否应该成为临床医生的目标值得怀疑。在一些研究中已经注意到短暂的血液动力学损害,少数研究报告了募集手法对持续性、有害的后果。尚未找到评估募集手法对通气时间、住院时间、发病率或死亡率影响的研究。募集手法通过克服阈开启压力来恢复呼气末肺容积,在断开回路和气道吸引后应用效果最佳。这最终是否能改善成人或儿科患者的预后尚不清楚。

相似文献

1
Lung recruitment--a guide for clinicians.肺复张策略——临床医生指南
Aust Crit Care. 2009 Nov;22(4):155-62. doi: 10.1016/j.aucc.2009.06.004. Epub 2009 Aug 12.
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[Alveolar ventilation and recruitment under lung protective ventilation].[肺保护性通气下的肺泡通气与肺复张]
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Crit Care Med. 2004 Jan;32(1):168-74. doi: 10.1097/01.CCM.0000104203.20830.AE.
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Lung-protective ventilation in neonatology.新生儿肺保护性通气策略。
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The effects of the alveolar recruitment maneuver and positive end-expiratory pressure on arterial oxygenation during laparoscopic bariatric surgery.腹腔镜减肥手术期间肺泡复张手法和呼气末正压对动脉氧合的影响。
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Positive end-expiratory pressure-induced functional recruitment in patients with acute respiratory distress syndrome.呼气末正压通气诱导急性呼吸窘迫综合征患者的功能复张。
Crit Care Med. 2010 Jan;38(1):127-32. doi: 10.1097/CCM.0b013e3181b4a7e7.

引用本文的文献

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Lung recruitment manoeuvres for reducing mortality and respiratory morbidity in mechanically ventilated neonates.肺复张手法用于降低机械通气新生儿的死亡率和呼吸发病率。
Cochrane Database Syst Rev. 2021 Mar 30;3(3):CD009969. doi: 10.1002/14651858.CD009969.pub2.