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慢性闭角型青光眼和正常眼压性青光眼的视神经乳头形态学特征

Optic nerve head morphologic characteristics in chronic angle-closure glaucoma and normal-tension glaucoma.

作者信息

Zhao Lin, Wu Lingling, Wang Xin

机构信息

Department of Ophthalmology, Peking University Third Hospital, Peking University Eye Center, Beijing, China.

出版信息

J Glaucoma. 2009 Aug;18(6):460-3. doi: 10.1097/IJG.0b013e31818c6f1a.

Abstract

PURPOSE

To determine whether the morphometric features of the optic disk in eyes with chronic angle-closure glaucoma (CACG) are different from those with normal-tension glaucoma (NTG).

PATIENTS AND METHODS

This is a retrospective, case-matched study. Patients with CACG or NTG in an early or moderate stage were recruited. On the basis of age, sex, and visual field mean defect, patients with CACG were matched to those with NTG on a case-by-case basis. Heidelberg retina tomography was used to evaluate the optic disk, and parameters were compared between the 2 groups.

RESULTS

Sixty-three patients were recruited for the study. Twenty cases (eyes) with CACG were matched to 20 cases (eyes) with NTG. The total, temporal/inferior, nasal/superior, and nasal/inferior rim area of the optic disk were significantly larger (P<0.05) in the CACG group. In patients with CACG rather than NTG, the cup volume in total and in each sector (except temporal) was significantly smaller (P=0.007 to 0.041). In patients with CACG rather than NTG, the mean cup depth and cup shape measure of the optic disk in total and in each sector (except temporal and temporal/inferior) were smaller (P=0.002 to 0.054).

CONCLUSIONS

The morphometric features of the optic disk in eyes with CACG are different from those with NTG.

摘要

目的

确定慢性闭角型青光眼(CACG)患者视盘的形态学特征是否与正常眼压性青光眼(NTG)患者不同。

患者与方法

这是一项回顾性病例对照研究。招募早期或中期的CACG或NTG患者。根据年龄、性别和视野平均缺损情况,将CACG患者与NTG患者逐例匹配。使用海德堡视网膜断层扫描评估视盘,并比较两组之间的参数。

结果

63例患者纳入研究。20例(眼)CACG患者与20例(眼)NTG患者匹配。CACG组视盘的总、颞侧/下方、鼻侧/上方以及鼻侧/下方边缘面积显著更大(P<0.05)。与NTG患者相比,CACG患者的总杯体积以及各象限(颞侧除外)的杯体积显著更小(P=0.007至0.041)。与NTG患者相比,CACG患者视盘的总平均杯深和杯形状测量值以及各象限(颞侧和颞侧/下方除外)的测量值更小(P=0.002至0.054)。

结论

CACG患者视盘的形态学特征与NTG患者不同。

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