Department of Bioscience and Oral Diagnosis, School of Dentistry of São José dos Campos. UNESP-Universidade Estadual Paulista, São José dos Campos, SP, Brazil CEP: 12245-000.
Med Oral Patol Oral Cir Bucal. 2009 Dec 1;14(12):e650-3. doi: 10.4317/medoral.14.e650.
Ameloblastic fibro-odontoma (AFO) is a rare, benign, slow-growing odontogenic tumor, generally asymptomatic and more prevalent in children and adolescents. We report a case of AFO in the mandible of an eight-year-old Caucasian male patient, and review the literature . Intraoral examination revealed a swelling extending from the deciduous second molar to the retromolar triangle, covered with normal mucosa. A panoramic radiograph showed a large, well-demarcated radiolucency with radiopaque areas. The provisional diagnosis was of AFO, and so an incisional biopsy was performed. Histologically, the lesion was composed of connective tissue resembling the dental papilla, with epithelial strands or islands, as well as denticles and amorphous masses of enamel and dentin consistent with a diagnosis of AFO. Surgical excision and curettage of the lesion were performed. The patient has been monitored for eight years and the lesion has not recurred.
成釉细胞纤维牙瘤(AFO)是一种罕见的良性、生长缓慢的牙源性肿瘤,通常无症状,多见于儿童和青少年。我们报告了一例发生在下颌骨的 AFO 病例,并对文献进行了回顾。口腔检查显示从乳牙第二磨牙到磨牙后三角区有肿胀,覆盖正常黏膜。全景片显示一个大的、界限清楚的透光区,伴有不透射线区域。初步诊断为 AFO,因此进行了切开活检。组织学上,病变由类似于牙乳头的结缔组织组成,有上皮条索或小岛,以及牙质和釉质的小齿和无定形团块,符合 AFO 的诊断。对病变进行了手术切除和刮除。患者已随访 8 年,病变未复发。