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抗血小板治疗患者的拔牙。纳瓦拉卫生服务局(西班牙)口腔健康部进行的一项研究。

Dental extractions in patients on antiplatelet therapy. A study conducted by the Oral Health Department of the Navarre Health Service (Spain).

机构信息

Oral Health Department, Navarre Health Service-Osasunbidea, Pamplona, Spain.

出版信息

Med Oral Patol Oral Cir Bucal. 2009 Nov 1;14(11):e588-92. doi: 10.4317/medoral.14.e588.

Abstract

OBJECTIVES

Antiplatelet drugs are used to treat and prevent a wide range of cardiovascular pathologies and/or cerebrovascular accidents. Although the use of anticoagulants in dental extractions is highly protocolized, a clear control method has not yet been established for antiplatelet drugs. This study is directed at evaluating the clinical consequences of extractions in patients on antiplatelet therapy.

STUDY DESIGN

The Oral Health Department of the Navarre Health Service-Osasunbidea conducted a trial on 155 patients who underwent dental extractions and were receiving antiplatelet therapy. The patients were not requested to interrupt the medication and local measures were taken to control potential haemorrhage.

RESULTS

No major haemorrhages were reported. One patient had a moderate haemorrhage that required emergency care. In the remaining patients the bleeding was controlled with local measures. With regard to subsequent bleeding, no differences were observed between the various antiplatelet drugs used. The only statistically significant relationship found was between bleeding and the number of teeth extracted.

CONCLUSIONS

It can be concluded that no more than 3 teeth should be removed at any one time, and for multiple extractions, the teeth should be adjacent to each other.

摘要

目的

抗血小板药物用于治疗和预防广泛的心血管病理和/或脑血管意外。尽管在拔牙中使用抗凝剂已高度规范化,但尚未为抗血小板药物建立明确的控制方法。本研究旨在评估接受抗血小板治疗的患者拔牙的临床后果。

研究设计

纳瓦拉卫生服务局-Osasunbidea 的口腔健康部门对 155 名接受抗血小板治疗并接受拔牙的患者进行了一项试验。未要求患者中断药物治疗,并采取局部措施控制潜在出血。

结果

未报告重大出血。一名患者出现中度出血,需要紧急护理。在其余患者中,通过局部措施控制了出血。关于随后的出血,使用的各种抗血小板药物之间未观察到差异。唯一发现的具有统计学意义的关系是出血与拔牙数量之间的关系。

结论

可以得出结论,每次拔牙不应超过 3 颗,对于多颗拔牙,牙齿应彼此相邻。

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