Monnier Florian, Taillefer Marc
CNRS, UMR 5253, Institut Charles Gerhardt Montpellier, Architectures Moléculaires et Matériaux Nanostructurés, ENSCM, 8, rue de l'Ecole Normale, 34296 Montpellier Cedex 5, France.
Angew Chem Int Ed Engl. 2009;48(38):6954-71. doi: 10.1002/anie.200804497.
Copper-catalyzed Ullmann condensations are key reactions for the formation of carbon-heteroatom and carbon-carbon bonds in organic synthesis. These reactions can lead to structural moieties that are prevalent in building blocks of active molecules in the life sciences and in many material precursors. An increasing number of publications have appeared concerning Ullmann-type intermolecular reactions for the coupling of aryl and vinyl halides with N, O, and C nucleophiles, and this Minireview highlights recent and major developments in this topic since 2004.
铜催化的乌尔曼缩合反应是有机合成中形成碳-杂原子键和碳-碳键的关键反应。这些反应能够生成在生命科学中活性分子的结构单元以及许多材料前驱体中普遍存在的结构部分。关于芳基卤化物和乙烯基卤化物与氮、氧和碳亲核试剂偶联的乌尔曼型分子间反应，已有越来越多的出版物问世，本综述重点介绍了自2004年以来该主题的近期重大进展。
