Momin Saira B, Del Rosso James Q, Michaels Brent, Mobini Narciss
Valley Hospital Medical Center/Touro University College of Osteopathic Medicine, Las Vegas, Nevada, USA.
Cutis. 2009 Jun;83(6):291-8.
Acute generalized exanthematous pustulosis (AGEP) is a diffuse pustular disorder that is primarily drug induced and characterized by acute, extensive, small, nonfollicular, sterile pustules that usually begin in intertriginous folds with widespread edema and erythema. This article reports a case in which thalidomide, dexamethasone, or meloxicam may have been the etiologic agent to induce AGEP and the skin condition may have worsened with administration of additional medications during hospital admission. A good thorough medical history, including a drug history, along with clinicopathologic correlation is extremely important in a patient presenting with acute diffuse pustular lesions.
急性泛发性脓疱病（AGEP）是一种弥漫性脓疱性疾病，主要由药物引起，其特征为急性、广泛、微小、非毛囊性、无菌性脓疱，通常始于皮肤褶皱处，伴有广泛水肿和红斑。本文报告了一例病例，其中沙利度胺、地塞米松或美洛昔康可能是诱发AGEP的病因，且在住院期间使用其他药物后皮肤状况可能恶化。对于出现急性弥漫性脓疱性病变的患者，详细全面的病史，包括用药史，以及临床病理相关性极为重要。
