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营养蛋白质组学与生物标志物发现

Nutrition proteomics and biomarker discovery.

作者信息

de Roos Baukje

出版信息

Expert Rev Proteomics. 2009 Aug;6(4):349-51. doi: 10.1586/epr.09.52.

DOI:10.1586/epr.09.52
PMID:19681670
Abstract

Baukje de Roos is a principal investigator at the University of Aberdeen, Rowett Institute of Nutrition and Health. She investigates mechanisms through which dietary fats and fatty acids, and also polyphenols, affect parameters involved in the development of heart disease in vivo. This is achieved not only by measuring their effect on conventional risk markers for heart disease but also by assessing their effect on new markers that are being developed through proteomic and mass spectrometry methods. She obtained her PhD in Human Nutrition at Wageningen University, The Netherlands, in January 2000, after which she was appointed as a post-doctoral research fellow at the Department of Vascular Biochemistry, Glasgow Royal Infirmary, in collaboration with GlaxoSmithKline. In June 2001 she joined the Rowett Research Institute in Aberdeen. She is currently working for the University of Aberdeen, where her research is funded by the Scottish Government Rural and Environment Research and Analysis Directorate (RERAD). She is an active member of the European Nutrigenomics Organisation (NuGO), an EU-funded Network of Excellence, which merges the nutrigenomics activities of its 23 partners across Europe.

摘要

鲍克耶·德罗os是阿伯丁大学罗维特营养与健康研究所的首席研究员。她研究膳食脂肪、脂肪酸以及多酚类物质在体内影响心脏病发展相关参数的机制。这不仅通过测量它们对心脏病传统风险标志物的影响来实现,还通过评估它们对通过蛋白质组学和质谱方法开发的新标志物的影响来实现。2000年1月,她在荷兰瓦赫宁根大学获得人类营养学博士学位,之后她被任命为格拉斯哥皇家医院血管生物化学系的博士后研究员,与葛兰素史克公司合作。2001年6月,她加入了阿伯丁的罗维特研究所。她目前在阿伯丁大学工作,其研究由苏格兰政府农村与环境研究与分析局(RERAD)资助。她是欧洲营养基因组学组织(NuGO)的活跃成员,NuGO是一个由欧盟资助的卓越网络,汇集了其在欧洲的23个合作伙伴的营养基因组学活动。

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