Department of Anaesthesia and Intensive Care Medicine, The Danish Poison Information Centre, Bispebjerg University Hospital, Bispebjerg Bakke 23, 60.1, Copenhagen, Denmark.
Acta Anaesthesiol Scand. 2009 Nov;53(10):1361-4. doi: 10.1111/j.1399-6576.2009.02083.x. Epub 2009 Aug 13.
A 24-year-old man was bit on the tongue by a European common adder. Within 15 min following envenomation, he experienced tongue swelling, hypotension and impaired consciousness. Antihistamine, corticosteroid and crystalloids were administered. Within 105 min of envenomation, increasing oral, pharyngeal and facial oedema compromised the airway, leading to respiratory failure, concomitant with circulatory failure related to hypoxaemia and systemic toxic effects. Acute tracheotomy secured the airway, and two doses of antivenom successfully treated the systemic, toxic effects. The reaction was severe due to rapid and suspected high-dose uptake of venom, underlining the need for early advanced symptomatic treatment with airway control and early and eventually repeated dosing of antivenom.
一名 24 岁男性被欧洲普通蝰蛇咬伤舌头。咬伤后 15 分钟内,他出现舌肿胀、低血压和意识障碍。给予抗组胺药、皮质类固醇和晶体液。咬伤后 105 分钟,口腔、咽和面部水肿逐渐加重,导致气道阻塞,出现呼吸衰竭,并伴有低氧血症和全身中毒引起的循环衰竭。急性气管切开术确保了气道通畅,两剂抗蛇毒血清成功治疗了全身中毒症状。由于毒液快速吸收且疑似高剂量,导致反应严重,这强调了早期进行高级对症治疗以控制气道,并尽早且最终重复使用抗蛇毒血清的必要性。