我们应该对戒烟治疗的效果有多大信心？
How confident should we be that smoking cessation treatments work?
机构信息
Departments of Psychiatry, Psychology and Family Practice, University of Vermont, Burlington, VT 05401, USA.
出版信息
Addiction. 2009 Oct;104(10):1637-40. doi: 10.1111/j.1360-0443.2009.02645.x. Epub 2009 Aug 4.
AIM
To determine (i) the concordance among recent meta-analyses about which treatments for smoking cessation are efficacious; (ii) the similarity of odds ratios (ORs) across meta-analyses; and (iii) among the validated treatments, the proportion of studies that found higher quit rates.
METHODS
Computerized literature search for meta-analyses during the last 5 years in PubMed and PsychInfo. Data were extracted from summary tables of overall effect of validated treatments.
RESULTS
Fourteen meta-analyses agreed 100% on the presence/absence of efficacy of 17 proven treatments. The ORs differed by <0.5 in 72/76 of the comparisons of meta-analyses. Among 37 comparisons in 33 comparisons, >85% of the studies reported numerical superiority for the active treatment.
CONCLUSIONS
The efficacy of treatments for smoking cessation are extremely reliable. This argues for inclusion of treatment as an essential feature of tobacco control and clinical practice and argues for reimbursement of smoking cessation treatments on a par with other medical and behavioral disorders.
目的
确定（i）最近关于哪些戒烟治疗方法有效的荟萃分析之间的一致性；（ii）荟萃分析之间的优势比（OR）的相似性；以及（iii）在经过验证的治疗方法中，发现更高戒烟率的研究比例。
方法
在 PubMed 和 PsychInfo 中进行了过去 5 年的荟萃分析计算机检索。从已验证治疗方法的总体效果汇总表中提取数据。
结果
14 项荟萃分析对 17 种已证实治疗方法的有效性的存在/不存在完全一致。在 76 次荟萃分析比较中，有 72 次的 OR 差异小于 0.5。在 33 次比较中的 37 次比较中，超过 85%的研究报告了活性治疗的数值优势。
结论
戒烟治疗的疗效非常可靠。这表明治疗应作为烟草控制和临床实践的基本特征之一，并应与其他医学和行为障碍一样，为戒烟治疗提供报销。
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