Department of Psychiatry and Behavioral Sciences and Hollings Cancer Center, Medical University of South Carolina, Charleston, SC;
Nicotine Tob Res. 2014 Apr;16(4):397-405. doi: 10.1093/ntr/ntt161. Epub 2013 Oct 15.
Low-nitrosamine smokeless tobacco (SLT) may have efficacy for smoking reduction and cessation, but its public health impact depends on how smokers use it.
This pilot study explored brief, instructional low-nitrosamine SLT use among smokers unmotivated to quit. Participants (N = 57) were randomized to either a free 2-week supply of Camel Snus group or a no-supply group. Of those randomized to use Camel Snus, half were told to use it to cope with smoking restrictions (Snus to Cope), and the remaining half were advised to use it to reduce smoking (Snus to Reduce). Participants were assessed before, during, and immediately after the intervention.
Many Snus to Cope and Snus to Reduce participants reported daily use of Camel Snus, although the amount of use was low. Snus to Cope (18.4%) and Snus to Reduce (37.6%) participants reported a decline in number of cigarettes used per day, which was not reported by the control participants (p < .001). Intention to quit smoking and intention to quit all tobacco use (ps < .001) increased to a greater extent among Snus to Cope and Snus to Reduce participants than among control participants.
This study replicates previous work that shows that low-nitrosamine SLT use can lead to reduced smoking and increased intention to quit, and it adds direct evidence to suggest that the function of low-nitrosamine SLT use-either to cope with smoking restrictions or to reduce smoking-can have a differential impact on smoking behavior. Overall, the results highlight the importance of messaging and, more specifically, marketing of low-nitrosamine SLT to smokers.
低亚硝胺含量无烟气烟草(SLT)可能对减少和戒烟有一定效果,但它对公共健康的影响取决于吸烟者如何使用它。
这项初步研究探索了动机不强的吸烟者使用简短的、指导性的低亚硝胺 SLT。参与者(N=57)被随机分配到免费提供为期两周 Camel Snus 的组或无供应组。在随机使用 Camel Snus 的参与者中,一半被告知使用它来应对吸烟限制(Snus to Cope),另一半则被建议使用它来减少吸烟(Snus to Reduce)。参与者在干预前、干预中和干预后立即进行评估。
许多 Snus to Cope 和 Snus to Reduce 参与者报告了每天使用 Camel Snus,尽管使用量很低。Snus to Cope(18.4%)和 Snus to Reduce(37.6%)参与者报告每天使用的香烟数量减少,而对照组参与者则没有报告(p<.001)。Snus to Cope 和 Snus to Reduce 参与者戒烟的意愿和戒烟的意愿(p<.001)比对照组参与者增加得更多。
这项研究复制了以前的工作,表明低亚硝胺 SLT 的使用可以减少吸烟和增加戒烟的意愿,并且它提供了直接的证据表明,低亚硝胺 SLT 的使用功能,无论是应对吸烟限制还是减少吸烟,都可以对吸烟行为产生不同的影响。总的来说,结果强调了向吸烟者宣传和更具体地宣传低亚硝胺 SLT 的重要性。