Department of Internal Medicine of Cardiology, National Taiwan University Hospital, Taipei, Taiwan.
Indoor Air. 2009 Dec;19(6):482-8. doi: 10.1111/j.1600-0668.2009.00612.x. Epub 2009 Jun 22.
This study aims to evaluate whether indoor particles are associated with elevated blood pressure (BP) and heart rate (HR). We recruited 40 young, healthy students from universities in Taipei. We made four home visits in which we took consecutive 48-h measurements of systolic BP, (SBP) diastolic BP (DBP), and HR in each participant. Particulate matter less than 10 microm in diameter (PM(10)), 2.5 microm in diameter (PM(2.5)), and nitrogen dioxide levels were measured at each participant's home. Participants were asked to keep their windows open during the first two visits, and keep their windows shut during the last two visits. We used linear mixed-effects models to associate BP and HR with indoor air pollutants averaged over 1- to 8-h periods prior to physiological measurements. We found indoor PM(10) and PM(2.5) exposures at 1- to 4-h means were associated with an elevation in SBP, DBP, and HR. Effects of indoor PM(10) and PM(2.5) on BP and HR were greatest during the visits with windows open. During windows-closed visits, participants showed no significant change in BP and HR with indoor PM(10) exposure. We concluded that exposures to infiltrated outdoor particles are associated with short-term increases in BP and HR in young and healthy students. Closing windows can reduce indoor PM concentrations and modify the effect of PM(10) on BP and HR in young adults.
Particulate matter exposure, high blood pressure (BP) and heart rate (HR) have been reported to be associated with increased risk of cardiovascular morbidity and mortality. Exposure to indoor particles is found to be associated with Elevated BP and HR. Closing windows may reduce indoor particles concentrations and modify the effect of particles on BP and HR in young adults in heavily polluted cities.
本研究旨在评估室内颗粒物是否与血压（BP）和心率（HR）升高有关。我们招募了来自台北大学的 40 名年轻健康的学生。我们进行了四次家访，在每次家访中连续测量了 48 小时每位参与者的收缩压（SBP）、舒张压（DBP）和 HR。在每位参与者的家中测量了直径小于 10 微米的颗粒物（PM（10））、2.5 微米的颗粒物（PM（2.5））和二氧化氮水平。要求参与者在前两次家访期间开窗，在后两次家访期间关窗。我们使用线性混合效应模型，将 BP 和 HR 与生理测量前 1 至 8 小时内的室内空气污染物平均值相关联。我们发现，1 至 4 小时的室内 PM（10）和 PM（2.5）暴露与 SBP、DBP 和 HR 的升高有关。在开窗家访期间，室内 PM（10）和 PM（2.5）对 BP 和 HR 的影响最大。在关窗家访期间，参与者的 BP 和 HR 随室内 PM（10）暴露无明显变化。我们的结论是，暴露于渗透的室外颗粒物与年轻健康学生的短期血压和心率升高有关。关闭窗户可以降低室内 PM 浓度，并改变 PM（10）对年轻成年人 BP 和 HR 的影响。
颗粒物暴露、高血压（BP）和心率（HR）已被报道与心血管发病率和死亡率增加有关。室内颗粒物暴露与 BP 和 HR 升高有关。在污染严重的城市，关闭窗户可能会降低室内颗粒物浓度，并改变颗粒物对年轻成年人 BP 和 HR 的影响。
