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室内气态空气污染与肥胖之间的正相关关系:60 户家庭的观察研究。

Positive Association between Indoor Gaseous Air Pollution and Obesity: An Observational Study in 60 Households.

机构信息

Institute of Environmental and Occupational Health Sciences, College of Public Health, National Taiwan University, Taipei 10055, Taiwan.

Global Health Program, College of Public Health, National Taiwan University, Taipei 10055, Taiwan.

出版信息

Int J Environ Res Public Health. 2021 Oct 30;18(21):11447. doi: 10.3390/ijerph182111447.

DOI:10.3390/ijerph182111447
PMID:34769965
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8582717/
Abstract

This study aims to analyze whether exposure to indoor air pollution affects obesity. In our research, we recruited 127 participants, with an average age of 43.30 ± 15.38 years old, residing in 60 households. We monitored indoor air quality for 24 h, and conducted both questionnaire surveys and collected serum samples for analysis, to assess the relationship between indoor air pollutant exposure and obesity. After adjusting for demographic characteristics, the results showed that CO exposure is positively associated with being overweight and with a higher risk of being abdominally obese. Exposures to CO and formaldehyde were also positively associated with being overweight. IQR increase in TVOC was positively associated with increases in the risk of a high BMI, being abdominally obese and having a high body fat percentage. Two-pollutant models demonstrate that TVOCs presented the strongest risks associated with overweightness. We concluded that persistent exposure to indoor gaseous pollutants increases the risk of overweightness and obesity, as indicated by the positive association with BMI, abdominal obesity, and percentage body fat. TVOCs display the strongest contribution to obesity.

摘要

本研究旨在分析室内空气污染暴露是否会影响肥胖。我们的研究招募了 127 名参与者,平均年龄为 43.30±15.38 岁,居住在 60 户家庭中。我们监测了 24 小时的室内空气质量,并进行了问卷调查和采集血清样本进行分析,以评估室内空气污染物暴露与肥胖之间的关系。在调整了人口统计学特征后,结果表明,CO 暴露与超重和腹部肥胖风险增加呈正相关。CO 和甲醛的暴露也与超重呈正相关。IQR 增加的 TVOC 与 BMI 升高、腹部肥胖和体脂百分比升高的风险呈正相关。双污染物模型表明,TVOCs 与超重之间存在最强的关联风险。我们得出结论,持续暴露于室内气态污染物会增加超重和肥胖的风险,这与 BMI、腹部肥胖和体脂百分比呈正相关。TVOCs 对肥胖的贡献最大。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5af/8582717/7644a86e4784/ijerph-18-11447-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5af/8582717/96410e685c58/ijerph-18-11447-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5af/8582717/7644a86e4784/ijerph-18-11447-g002a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5af/8582717/96410e685c58/ijerph-18-11447-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e5af/8582717/7644a86e4784/ijerph-18-11447-g002a.jpg

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J Health Pollut. 2021 May 28;11(30):210610. doi: 10.5696/2156-9614-11.30.210610. eCollection 2021 Jun.
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Early-Life Environmental Exposures and Childhood Obesity: An Exposome-Wide Approach.早期生活环境暴露与儿童肥胖:暴露组学全基因组关联研究方法。
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