Hamilton Rebekah
Department of Women, Children and Family Health Science, College of Nursing, University of Illinois at Chicago, Chicago, IL 60612, USA.
Nurs Clin North Am. 2009 Sep;44(3):327-38. doi: 10.1016/j.cnur.2009.06.004.
Genetic testing for adult-onset diseases is now available. One such test is for the mutations present in the BRCA gene that result in a significantly higher risk for the development of breast cancer or ovarian cancer. Women who have one of these mutations face difficult choices in terms of increased surveillance or prophylactic surgeries. Examining experiences of women with BRCA mutations can serve as an exemplar for other populations at risk for genetically associated adult-onset diseases.
现在可以进行成人发病疾病的基因检测。其中一种检测是针对BRCA基因中存在的突变，这些突变会导致患乳腺癌或卵巢癌的风险显著增加。携带这些突变之一的女性在加强监测或预防性手术方面面临艰难抉择。研究携带BRCA突变的女性的经历可以为其他有患成人发病的基因相关疾病风险的人群提供范例。
