Department of Urology, Zonguldak Karaelmas University Faculty of Medicine, Zonguldak, Turkey.
Fertil Steril. 2010 Jan;93(1):280-2. doi: 10.1016/j.fertnstert.2009.07.981. Epub 2009 Aug 14.
In this experimental study, we assessed the preventive effects of coenzyme Q(10) (CoQ(10)) in a rat model of ischemia/reperfusion injury. The results of this study show that CoQ(10) administration before the reperfusion period of testicular torsion provides a significant decrease in testicular lipid peroxidation products and expressions of inducible nitric oxide synthase, endothelial nitric oxide synthase, and germ cell-specific apoptosis.
在这项实验研究中，我们评估了辅酶 Q(10)（CoQ(10)）在缺血/再灌注损伤大鼠模型中的预防作用。本研究结果表明，CoQ(10)在睾丸扭转再灌注期前给药可显著减少睾丸脂质过氧化产物以及诱导型一氧化氮合酶、内皮型一氧化氮合酶和生殖细胞特异性凋亡的表达。
