使用加速度计对伴有和不伴有周围神经病变的糖尿病患者的站立平衡进行研究。
Investigation of standing balance in diabetic patients with and without peripheral neuropathy using accelerometers.
作者信息
Turcot K, Allet L, Golay A, Hoffmeyer P, Armand S
机构信息
Willy Taillard Laboratory of Kinesiology, Geneva University Hospitals and Geneva University, 1211 Geneva 14, Switzerland.
出版信息
Clin Biomech (Bristol). 2009 Nov;24(9):716-21. doi: 10.1016/j.clinbiomech.2009.07.003. Epub 2009 Aug 14.
BACKGROUND
Peripheral neuropathy is recognised to be the most symptomatic complication of diabetes and is also linked to postural instability. This study investigates balance instability in diabetic patients with and without peripheral neuropathy.
METHODS
Quiet standing balance was investigated using an accelerometric-based method in 24 diabetic patients (12 with and 12 without peripheral neuropathy) and compared with 12 control subjects. Accelerations were measured at lumbar and ankle levels using three accelerometers. Two standing conditions of 30s were evaluated (i.e., eyes opened, eyes closed). The range and root mean square values were calculated on the anterior posterior component of lumbar and ankle accelerations and for the medial lateral component of lumbar accelerations. Differences between parameters were compared between groups using ANOVA and post hoc comparisons.
FINDINGS
The diabetic patients with peripheral neuropathy show higher-range and root mean square values compared with those of control subjects and diabetic patients without peripheral neuropathy. Significant differences between groups have been detected for anterior posterior range of lumbar acceleration, which was significantly higher for diabetic patients with peripheral neuropathy, compared with those of others groups. Significant higher values for diabetic patients with peripheral neuropathy were also detected for anterior posterior range and root mean square of ankle accelerations compared with control subjects. Visual deprivation shows an increase in accelerometric parameters for each group.
INTERPRETATION
This study is the first to investigate the balance instability of diabetic patients using accelerometers. Results confirm that diabetic patients with peripheral neuropathy have greater postural instability with higher acceleration values than those of control group and diabetic patients without peripheral neuropathy.
背景
外周神经病变被认为是糖尿病最具症状性的并发症，且与姿势不稳有关。本研究调查了有和没有外周神经病变的糖尿病患者的平衡不稳情况。
方法
采用基于加速度测量的方法，对24名糖尿病患者（12名有外周神经病变，12名没有外周神经病变）的静立平衡进行了研究，并与12名对照受试者进行比较。使用三个加速度计在腰椎和踝关节水平测量加速度。评估了两种30秒的站立状态（即睁眼、闭眼）。计算了腰椎和踝关节加速度前后分量以及腰椎加速度内外侧分量的范围和均方根值。使用方差分析和事后比较对组间参数差异进行比较。
研究结果
与对照受试者和没有外周神经病变的糖尿病患者相比，有外周神经病变的糖尿病患者显示出更高的范围和均方根值。在腰椎加速度前后范围方面检测到组间存在显著差异，有外周神经病变的糖尿病患者的该值显著高于其他组。与对照受试者相比，有外周神经病变的糖尿病患者在踝关节加速度前后范围和均方根方面也检测到显著更高的值。视觉剥夺显示每组的加速度测量参数均增加。
解读
本研究首次使用加速度计调查糖尿病患者的平衡不稳情况。结果证实，与对照组和没有外周神经病变的糖尿病患者相比，有外周神经病变的糖尿病患者姿势不稳更严重，加速度值更高。
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