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本文引用的文献

1
Noninvasive measurement of local thermal diffusivity using backscattered ultrasound and focused ultrasound heating.利用背向散射超声和聚焦超声加热进行局部热扩散率的无创测量。
Ultrasound Med Biol. 2008 Sep;34(9):1449-64. doi: 10.1016/j.ultrasmedbio.2008.02.004. Epub 2008 May 1.
2
Feasibility of ultrasound phase contrast for heating localization.超声相衬用于热定位的可行性。
J Acoust Soc Am. 2008 Mar;123(3):1773-83. doi: 10.1121/1.2835438.
3
Current time-domain methods for assessing tissue motion by analysis from reflected ultrasound echoes-a review.通过反射超声回波分析评估组织运动的当前时域方法——综述
IEEE Trans Ultrason Ferroelectr Freq Control. 1993;40(2):84-102. doi: 10.1109/58.212556.
4
Two-dimensional temperature estimation using diagnostic ultrasound.使用诊断超声进行二维温度估计。
IEEE Trans Ultrason Ferroelectr Freq Control. 1998;45(4):1088-99. doi: 10.1109/58.710592.
5
MR thermometry.磁共振温度测量法
J Magn Reson Imaging. 2008 Feb;27(2):376-90. doi: 10.1002/jmri.21265.
6
Noninvasive estimation of temperature elevations in biological tissues using acoustic nonlinearity parameter imaging.使用声学非线性参数成像技术对生物组织中的温度升高进行无创估计。
Ultrasound Med Biol. 2008 Mar;34(3):414-24. doi: 10.1016/j.ultrasmedbio.2007.09.006. Epub 2008 Jan 9.
7
Non-invasive ultrasound-based temperature imaging for monitoring radiofrequency heating-phantom results.基于非侵入性超声的温度成像用于监测射频加热——体模结果。
Phys Med Biol. 2007 Aug 21;52(16):4827-43. doi: 10.1088/0031-9155/52/16/008. Epub 2007 Jul 30.
8
Three-dimensional spatial and temporal temperature imaging in gel phantoms using backscattered ultrasound.利用背向散射超声对凝胶体模进行三维空间和时间温度成像。
IEEE Trans Ultrason Ferroelectr Freq Control. 2007 Jan;54(1):23-31. doi: 10.1109/tuffc.2007.208.
9
Quantitative discrimination of pigmented lesions using three-dimensional high-resolution ultrasound reflex transmission imaging.使用三维高分辨率超声反射透射成像对色素沉着病变进行定量鉴别
J Invest Dermatol. 2007 Jan;127(1):189-95. doi: 10.1038/sj.jid.5700554. Epub 2006 Oct 26.
10
Quantitative MRI-based temperature mapping based on the proton resonant frequency shift: review of validation studies.基于质子共振频率偏移的定量磁共振成像温度映射：验证研究综述
Int J Hyperthermia. 2005 Sep;21(6):533-46. doi: 10.1080/02656730500096073.

超声相位对比热成像与组织体模中的反射传输成像方法。

Ultrasound phase contrast thermal imaging with reflex transmission imaging methods in tissue phantoms.

机构信息

Department of Radiology, Harvard Medical School, Brigham and Women's Hospital, Boston, MA 02115, USA.

出版信息

Ultrasound Med Biol. 2009 Dec;35(12):1995-2006. doi: 10.1016/j.ultrasmedbio.2009.05.019. Epub 2009 Aug 14.

DOI:10.1016/j.ultrasmedbio.2009.05.019
PMID:19683380
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2790025/
Abstract

Thermal imaging measurements using ultrasound phase contrast have been performed in tissue phantoms heated with a focused ultrasound source. Back projection and reflex transmission imaging principles were used to detect sound speed-induced changes in the phase caused by an increase in the temperature. The temperature was determined from an empirical relationship for the temperature dependence on sound speed. The phase contrast was determined from changes in the sound field measured with a hydrophone scan conducted before and during applied heating. The lengthy scanning routine used to mimic a large two-dimensional array required a steady-state temperature distribution within the phantom. The temperature distribution in the phantom was validated with magnetic resonance (MR) thermal imaging measurements. The peak temperature was found to agree within 1 degrees C with MR, and good agreement was found between the temperature profiles. The spatial resolution was 0.3x0.3x0.3mm, comparing favorably with the 0.625x0.625x1.5-mm MR spatial resolution.

摘要

利用超声相位对比进行的热成像测量已在使用聚焦超声源加热的组织模型中进行。采用背投影和反射传输成像原理来检测由于温度升高而导致相位中声速变化引起的变化。温度是根据声速随温度的变化关系确定的。通过在施加加热前后使用水听器扫描测量声场的变化来确定相位对比度。为了模拟大型二维阵列，使用了冗长的扫描程序，这需要在模型中具有稳定的温度分布。使用磁共振（MR）热成像测量验证了模型中的温度分布。发现峰值温度与 MR 相差 1 摄氏度以内，并且温度分布之间存在良好的一致性。空间分辨率为 0.3x0.3x0.3mm，与 0.625x0.625x1.5-mm MR 空间分辨率相比具有优势。