Pan Yi-Ju, Chen Sue-Huei, Chen Wei J, Liu Shi-Kai
Department of Psychiatry, National Taiwan University Hospital, Taipei, Taiwan.
Compr Psychiatry. 2009 Sep-Oct;50(5):443-52. doi: 10.1016/j.comppsych.2008.11.003. Epub 2009 Jan 20.
Facial affect recognition deficits may represent specific deficits and contribute to social dysfunction in patients with schizophrenia. Whether their impacts on social dysfunction are independent to those caused by deficits in basic neurocognition and clinical symptoms needs to be further delineated.
Association patterns between affect recognition and basic neurocognitive abilities in 40 acute and 33 stable patients with schizophrenia were compared to explore whether their interrelationships changed across clinical stages. The independent contribution of affect recognition deficits to social dysfunction was explored by multivariate models controlling for general intellectual ability, basic neurocognition, and clinical symptoms.
Affect recognition deficits were associated with social role performances, self-care, and contributed independently to global social functioning in stable patients but not in acute patients. Conversely, affect recognition deficits were associated with impaired basic neurocognitions in acute patients but not in stable patients.
In stabilized community patients with schizophrenia, affect recognition deficits were relatively independent to basic neurocognition and had significant social functional consequences.
面部表情识别缺陷可能代表特定缺陷，并导致精神分裂症患者的社会功能障碍。其对社会功能障碍的影响是否独立于基本神经认知缺陷和临床症状所造成的影响，仍有待进一步阐明。
比较了40例急性精神分裂症患者和33例稳定期精神分裂症患者的表情识别与基本神经认知能力之间的关联模式，以探讨它们的相互关系在不同临床阶段是否发生变化。通过控制一般智力能力、基本神经认知和临床症状的多变量模型，探讨了表情识别缺陷对社会功能障碍的独立影响。
表情识别缺陷与社会角色表现、自我护理相关，并且在稳定期患者中对整体社会功能有独立影响，但在急性期患者中并非如此。相反，表情识别缺陷与急性期患者的基本神经认知受损有关，但与稳定期患者无关。
在病情稳定的社区精神分裂症患者中，表情识别缺陷相对独立于基本神经认知，并且具有显著的社会功能后果。
