Mirone G, Bouazza S, Chibbaro S, Bresson D, Pavlika M, George B
Department of Neurosurgery, Lariboisiere Hospital, 75475 Paris Cedex 10, France.
J Clin Neurosci. 2009 Nov;16(11):1495-7. doi: 10.1016/j.jocn.2009.02.011. Epub 2009 Aug 15.
Malignant rhabdoid tumour (MRT) was described for the first time in the kidney, and is rarely reported in the brain. Most rhabdoid tumours affect infants and young children and there have been only isolated adult patients reported. The optimal treatment for this very aggressive tumour has not yet been established. We describe the clinical and pathological features of a rare primary malignant rhabdoid tumour of the brain in a 27-year-old pregnant female. The literature is reviewed briefly and the role of the INI1 gene in adult MRTs and the also possible interactions between MRTs and pregnancy are discussed.
恶性横纹肌样瘤（MRT）首次在肾脏中被描述，在脑部很少有报道。大多数横纹肌样瘤影响婴幼儿，仅有个别成年患者的报道。这种极具侵袭性的肿瘤的最佳治疗方法尚未确定。我们描述了一名27岁怀孕女性罕见的原发性脑恶性横纹肌样瘤的临床和病理特征。简要回顾了文献，并讨论了INI1基因在成人MRT中的作用以及MRT与妊娠之间可能的相互作用。
