Raniga Aparna, Elder Mark J
Ophthalmology, Christchurch Hospital, Christchurch, New Zealand.
N Z Med J. 2009 Jul 24;122(1299):32-8.
The Age-Related Eye Disease Study Group (AREDS) has found high-dose vitamin supplementation may have a role in preventing the progression of Category 3 and 4 age-related maculopathy. The aim of this study is to compare dietary antioxidant, zinc, and copper intakes of Australia, New Zealand, United Kingdom, and the United States to determine the difference between the actual and suggested AREDS intakes for these nutrients. A further aim is to investigate the constituents of commonly available single and multivitamin preparations in New Zealand and carry out a cost analysis.
The total median intake of vitamins A, C, and E; zinc; and copper is analysed from the most recent nutrition data published by the four countries. Forty multivitamin brands and 32 individual nutrient brands were analysed. An average price per tablet for each brand has been calculated in New Zealand dollars.
The median intakes of antioxidants, zinc, and copper for these countries were comparable, but lower than the AREDS suggested intakes. Sixteen of the 40 multivitamin preparations contained all recommended nutrients. Of these, only two fulfilled the AREDS-recommended levels. The cost of different preparations is similar.
Dietary supplementation is required to achieve the AREDS nutrient intake recommendations. This may be achieved by using any combination of multivitamin and individual supplement preparations available. Comprehensive tables have been constructed to guide ophthalmologists in the process of suggesting supplementation to prevent the progression of Category 3 and 4 age-related maculopathy.
年龄相关性眼病研究组（AREDS）发现高剂量维生素补充剂可能在预防3级和4级年龄相关性黄斑病变进展方面发挥作用。本研究的目的是比较澳大利亚、新西兰、英国和美国的膳食抗氧化剂、锌和铜摄入量，以确定这些营养素的实际摄入量与AREDS建议摄入量之间的差异。另一个目的是调查新西兰常见的单一和多种维生素制剂的成分，并进行成本分析。
从这四个国家公布的最新营养数据中分析维生素A、C和E、锌以及铜的总中位数摄入量。对40个多种维生素品牌和32个单一营养素品牌进行了分析。已计算出每个品牌每片的平均价格（以新西兰元计）。
这些国家抗氧化剂、锌和铜的中位数摄入量相当，但低于AREDS建议的摄入量。40种多种维生素制剂中有16种含有所有推荐营养素。其中，只有两种达到了AREDS推荐水平。不同制剂的成本相似。
需要通过膳食补充剂来达到AREDS的营养素摄入建议。这可以通过使用现有的多种维生素和单一补充剂制剂的任何组合来实现。已编制综合表格，以指导眼科医生在建议补充剂以预防3级和4级年龄相关性黄斑病变进展的过程中。
