Chemistry Department, New York University, New York City, New York 10003, USA.
Org Lett. 2009 Sep 17;11(18):4152-5. doi: 10.1021/ol9016645.
An easy one-pot procedure to synthesize rotaxanes bearing electron donors and C(60) is described. The straightforward strategy, based on copper(I)-templated synthesis and "click" chemistry, proved to be very efficient and versatile, allowing the preparation of porphyrin- and ferrocene-stoppered fullerene-rotaxanes in high yields. As revealed by NMR analysis and computational studies, the highly flexible porphyrin-fullerene rotaxane can assume different conformations, which are most likely driven by attractive interactions between porphyrin and fullerene moieties.
描述了一种简便的一锅法合成带有电子给体和 C(60)的轮烷的方法。该方法基于铜（I）模板合成和“点击”化学，具有很高的效率和通用性，可高产率地制备卟啉和二茂铁封端的富勒烯轮烷。通过 NMR 分析和计算研究表明，高度灵活的卟啉-富勒烯轮烷可以采用不同的构象，这很可能是由卟啉和富勒烯部分之间的吸引力驱动的。
