嗅觉中的模式分离与完成
Pattern separation and completion in olfaction.
作者信息
Wilson Donald A
机构信息
Emotional Brain Institute, Nathan Kline Institute for Psychiatric Research, and Child and Adolescent Psychiatry, New York University School of Medicine, Orangeburg, New York 10962, USA.
出版信息
Ann N Y Acad Sci. 2009 Jul;1170:306-12. doi: 10.1111/j.1749-6632.2009.04017.x.
Abstract
The nervous system must provide a mechanism for very precise discrimination of differing patterns of activity, yet at the same time, there must be a mechanism for generalization to prevent all experiences from being independent and novel. Pattern separation and completion by cortical circuits contribute to these processes, respectively. Based on theoretical and computational models of the piriform cortex and experimental designs developed for hippocampal spatial memory, we provide evidence for pattern separation and completion in the olfactory system and demonstrate the predictive power of these two processes for behavioral odor perception.
摘要
神经系统必须提供一种机制，以便非常精确地区分不同的活动模式，但与此同时，还必须有一种泛化机制，以防止所有经历都相互独立且全新。皮层回路的模式分离和完成分别有助于这些过程。基于梨状皮层的理论和计算模型以及为海马体空间记忆开发的实验设计，我们提供了嗅觉系统中模式分离和完成的证据，并证明了这两个过程对行为气味感知的预测能力。
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