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肉毒杆菌毒素 A(肉毒素)用于缓解阴茎回缩。

Botulinum toxin a (Botox) for relieving penile retraction.

机构信息

Department of Andrology, Cairo University, Egypt, 21 Gaber Ibn Hayan Street, Dokki, Cairo 12311 ARE, Egypt.

出版信息

J Sex Med. 2009 Oct;6(10):2788-94. doi: 10.1111/j.1743-6109.2009.01434.x. Epub 2009 Aug 4.

DOI:10.1111/j.1743-6109.2009.01434.x
PMID:19686423
Abstract

INTRODUCTION

The flaccid penis undergoes retraction upon contraction of the dartos muscle. These contractions are most pronounced in the situations of cold, stress, and upon exercising, and can be the source of embarrassment to those who have a hyperactive retraction reflex, especially when exposed to their partners or to others in showers and dressing rooms, despite a normal and satisfactory length in the erect state.

AIM

In this work, we propose an alternative to surgery and penile extenders for alleviating penile retraction, by injection of botulinum toxin into the dartos to induce muscle relaxation. This is the first report of the technique.

METHODS

Ten male patients complaining of a short penis exclusively in the flaccid state, despite normal and satisfactory erect and outstretched lengths, were selected for the study. One hundred units of BOTOX were injected into the dartos muscle.

MAIN OUTCOME MEASURES

Frequency and amplitude of penile retraction, flaccid unstretched length, and patient satisfaction.

RESULTS

Seven out of 10 cases (70%) subjectively reported a decrease in the frequency and amplitude of penile retraction, as well as improvement in flaccid length. Clinical measurements were less pronounced but still showed an improvement that was mainly in terms of less retraction rather than more length. No side effects were reported. Improvement faded completely by the 6th month.

CONCLUSION

This preliminary report of botulinum toxin A (Botox) injection into the dartos muscle shows that Botox may have a potential effect in temporarily decreasing penile retractions in terms of frequency and amplitude.

摘要

简介

在提睾肌收缩时,疲软的阴茎会回缩。这些收缩在寒冷、紧张和运动时最为明显,对于那些有过度活跃的回缩反射的人来说,尤其是当他们在淋浴间或更衣室暴露给伴侣或其他人时,会感到尴尬,尽管他们在勃起状态下的长度正常且令人满意。

目的

在这项工作中,我们通过向提睾肌注射肉毒杆菌毒素来诱导肌肉放松,提出了一种替代手术和阴茎延长器的方法来缓解阴茎回缩。这是该技术的首次报道。

方法

选择 10 名男性患者,他们仅在疲软状态下抱怨阴茎短小,尽管勃起和伸展时长度正常且令人满意。向提睾肌注射 100 个单位的 BOTOX。

主要观察指标

阴茎回缩的频率和幅度、疲软未伸展长度和患者满意度。

结果

10 例中有 7 例(70%)主观报告阴茎回缩的频率和幅度降低,并且疲软长度得到改善。临床测量结果不太明显,但仍显示出主要是回缩减少而不是长度增加的改善。未报告任何副作用。改善在第 6 个月完全消退。

结论

本初步报告显示,向提睾肌注射肉毒杆菌毒素 A(Botox)可能具有暂时降低阴茎回缩频率和幅度的潜在效果。

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