Ozbölük S, Ozkan Y, Oztürk A, Gül N, Ozdemir R M, Yanik K
Bursa High Specialty Research and Training Hospital, Clinic of Orthopaedics and Traumatology Yildirim, Department of Surgery, Veterinary Faculty, Uludağ University, Görükle, Bursa, Turkey.
J Hand Surg Eur Vol. 2010 May;35(4):262-8. doi: 10.1177/1753193409337961. Epub 2009 Aug 17.
In this study, the effects of periosteal autograft and human amniotic membrane on tendon healing were compared. Forty-two New Zealand rabbits were divided into three groups. Flexor digitorum fibularis tendons were cut and repaired with a modified Kessler technique and circumferential sutures in all groups. Tendon repair alone was carried out in group 1, tendon repair and application of human amniotic membrane was done in group 2 and tendon repair and application of periosteal autograft was done in group 3. Biomechanical and histopathological examinations were done 2 and 6 weeks postoperatively. Biomechanical examination showed that group 3 was the strongest at weeks 2 and 6. Adhesion, inflammation and new bone formation showed no difference between groups at week 2. However, adhesion formation was found to be less in groups 2 and 3 than group 1 at week 6. The application of periosteal autograft might be useful in repair of tendon injuries.
在本研究中，比较了自体骨膜移植和人羊膜对肌腱愈合的影响。将42只新西兰兔分为三组。所有组均采用改良的凯斯勒技术和环形缝合切断并修复腓侧趾长屈肌腱。第1组仅进行肌腱修复，第2组进行肌腱修复并应用人羊膜，第3组进行肌腱修复并应用自体骨膜移植。术后2周和6周进行生物力学和组织病理学检查。生物力学检查显示，第3组在术后2周和6周时强度最大。术后2周时，各组之间的粘连、炎症和新骨形成无差异。然而，术后6周时发现第2组和第3组的粘连形成少于第1组。自体骨膜移植的应用可能有助于肌腱损伤的修复。
