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针对成年智障人士挑战性行为的专家行为治疗团队的随机、单盲对照试验。

Randomized, single-blind, controlled trial of a specialist behavior therapy team for challenging behavior in adults with intellectual disabilities.

作者信息

Hassiotis Angela, Robotham Dan, Canagasabey Anton, Romeo Renee, Langridge Diane, Blizard Robert, Murad Shahed, King Michael

机构信息

Department of Mental Health Sciences, University College London Medical School, UK.

出版信息

Am J Psychiatry. 2009 Nov;166(11):1278-85. doi: 10.1176/appi.ajp.2009.08111747. Epub 2009 Aug 17.

Abstract

OBJECTIVE

Community-based specialist behavior therapy teams may be helpful in managing challenging behavior, but evidence of their effectiveness is limited. This study was designed to examine the effectiveness and costs associated with treatment by a specialist behavior therapy team.

METHOD

This was a parallel-group, randomized, single-blind controlled trial carried out in an intellectual disabilities service in England. Participants were 63 male and female service users with mild to severe intellectual disability who presented with challenging behavior. The interventions were standard treatment plus applied behavioral analysis (N=32) and standard treatment only (N=31). The primary outcome measure was challenging behavior, as measured by total and subscale scores on the Aberrant Behavior Checklist 3 and 6 months after randomization. Secondary outcome measures were psychiatric comorbidity assessed at 3 and 6 months using the Psychiatric Assessment Schedule for Adults With a Developmental Disability Checklist (PAS-ADD) and total costs recorded at 6 months. Multilevel modeling was used to compare square root transformations of Aberrant Behavior Checklist scores.

RESULTS

Significant differences were found in the transformed total scores on the Aberrant Behavior Checklist (difference=-0.89, 95% CI=-1.74 to -0.04) and transformed lethargy and hyperactivity subscale scores (common intervention effect=-0.56, 95% CI=-0.97 to -0.15). Standard care participants fared worse on the PAS-ADD comorbid organic disorder subscale. There was a clear trend for lower overall costs of the intervention.

CONCLUSIONS

Use of a specialist behavior therapy team in addition to standard treatment appears to be more effective in improving challenging behavior and may have financial advantages over standard treatment.

摘要

目的

基于社区的专业行为治疗团队可能有助于管理具有挑战性的行为,但其有效性的证据有限。本研究旨在检验专业行为治疗团队治疗的有效性和成本。

方法

这是一项在英国一家智力残疾服务机构进行的平行组、随机、单盲对照试验。参与者为63名有轻度至重度智力残疾且表现出具有挑战性的行为的男性和女性服务使用者。干预措施为标准治疗加应用行为分析(N = 32)和仅标准治疗(N = 31)。主要结局指标为随机分组后3个月和6个月时通过异常行为检查表的总分及分量表得分测量的具有挑战性的行为。次要结局指标为使用发育障碍成人精神病评估检查表(PAS - ADD)在3个月和6个月时评估的精神科共病情况以及6个月时记录的总成本。采用多水平模型比较异常行为检查表得分的平方根转换值。

结果

在异常行为检查表的转换总分(差异=-0.89,95%CI=-1.74至-0.04)以及转换后的嗜睡和多动分量表得分(共同干预效应=-0.56,95%CI=-0.97至-0.15)方面发现了显著差异。标准护理参与者在PAS - ADD共病器质性障碍分量表上表现更差。干预的总体成本有明显的降低趋势。

结论

除标准治疗外使用专业行为治疗团队似乎在改善具有挑战性的行为方面更有效,并且可能比标准治疗具有经济优势。

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