Estia Centre, Institute of Psychiatry, King's College London, UK.
Res Dev Disabil. 2010 Mar-Apr;31(2):362-6. doi: 10.1016/j.ridd.2009.10.009. Epub 2009 Dec 1.
We investigated the relationship between challenging behavior and co-morbid psychopathology in adults with intellectual disability (ID) and autism spectrum disorders (ASDs) (N=124) as compared to adults with ID only (N=562). All participants were first time referrals to specialist mental health services and were living in community settings. Clinical diagnoses were based on ICD-10 criteria and presence of challenging behavior was assessed with the Disability Assessment Schedule (DAS-B). The analyses showed that ASD diagnosis was significantly associated with male gender, younger age and lower level of ID. Challenging behavior was about four times more likely in adults with ASD as compared to non-ASD adults. In those with challenging behavior, there were significant differences in co-morbid psychopathology between ASD and non-ASD adults. However, after controlling for level of ID, gender and age, there was no association between co-morbid psychopathology and presence of challenging behavior. Overall, the results suggest that presence of challenging behavior is independent from co-morbid psychopathology in adults with ID and ASD.
我们调查了智力障碍（ID）和自闭症谱系障碍（ASD）成人（N=124）与仅 ID 成人（N=562）之间的挑战性行为与共患精神病理学之间的关系。所有参与者均首次向专业心理健康服务机构转介，并居住在社区环境中。临床诊断基于 ICD-10 标准，使用残疾评估表（DAS-B）评估挑战性行为。分析表明，ASD 诊断与男性、年龄较小和 ID 水平较低显著相关。与非 ASD 成人相比，ASD 成人的挑战性行为可能性高四倍左右。在有挑战性行为的患者中，ASD 和非 ASD 成人的共患精神病理学存在显著差异。然而，在控制 ID 水平、性别和年龄后，共患精神病理学与挑战性行为的存在之间没有关联。总体而言，结果表明，ID 和 ASD 成人的挑战性行为与共患精神病理学无关。
