• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

钙通道阻滞剂中毒

Calcium channel blocker toxicity.

作者信息

Arroyo Anna Maria, Kao Louise W

机构信息

Medical Toxicology, Department of Emergency Medicine, Indiana University School of Medicine, Indianapolis, IN, USA.

出版信息

Pediatr Emerg Care. 2009 Aug;25(8):532-8; quiz 539-40. doi: 10.1097/PEC.0b013e3181b0a504.

DOI:10.1097/PEC.0b013e3181b0a504
PMID:19687715
Abstract

Calcium channel blockers continue to be used for the management of a wide variety of adult and pediatric conditions including hypertension, angina pectoris, atrial arrhythmias, Raynaud phenomenon, and migraine headaches. With increased use comes increased potential for misuse and abuse. This article serves as a review of calcium channel blocker physiology with emphasis on presentation and management of the pediatric patient with calcium channel blocker toxicity.

摘要

钙通道阻滞剂仍被用于治疗多种成人和儿童疾病,包括高血压、心绞痛、房性心律失常、雷诺现象和偏头痛。随着使用的增加,误用和滥用的可能性也在增加。本文旨在回顾钙通道阻滞剂的生理学,重点介绍小儿钙通道阻滞剂中毒的表现及处理。

相似文献

1
Calcium channel blocker toxicity.钙通道阻滞剂中毒
Pediatr Emerg Care. 2009 Aug;25(8):532-8; quiz 539-40. doi: 10.1097/PEC.0b013e3181b0a504.
2
[Beta-blocker and calcium antagonist poisoning. Two cardiological problems with an endocrinological solution?].[β受体阻滞剂和钙拮抗剂中毒。两个心脏病学问题却有一个内分泌学的解决办法?]
Ugeskr Laeger. 2004 Sep 27;166(40):3483-7.
3
High-dose insulin therapy for calcium-channel blocker overdose.高剂量胰岛素疗法用于钙通道阻滞剂过量中毒
Ann Pharmacother. 2005 May;39(5):923-30. doi: 10.1345/aph.1E436. Epub 2005 Apr 5.
4
Calcium channel blocker overdose.钙通道阻滞剂过量。
Am J Emerg Med. 1995 Jul;13(4):444-50. doi: 10.1016/0735-6757(95)90137-X.
5
Massive overdose of sustained-release verapamil: a case report and review of literature.缓释维拉帕米大量过量:一例病例报告及文献综述
Am J Med Sci. 1995 Dec;310(6):258-63.
6
Are one or two dangerous? Calcium channel blocker exposure in toddlers.
J Emerg Med. 2007 Aug;33(2):145-54. doi: 10.1016/j.jemermed.2007.02.010. Epub 2007 Jul 5.
7
Beta-blocker and calcium channel blocker toxicity.β受体阻滞剂与钙通道阻滞剂中毒
Emerg Med Clin North Am. 1994 May;12(2):365-90.
8
Intravenous fat emulsion therapy for intentional sustained-release verapamil overdose.静脉脂肪乳剂治疗维拉帕米缓释制剂故意过量服用。
Resuscitation. 2009 May;80(5):591-3. doi: 10.1016/j.resuscitation.2009.01.023. Epub 2009 Mar 17.
9
Comparative clinical pharmacology of calcium channel blockers.钙通道阻滞剂的比较临床药理学
Am Fam Physician. 1991 Feb;43(2):583-8.
10
Management of beta-adrenergic blocker and calcium channel antagonist toxicity.β-肾上腺素能阻滞剂和钙通道拮抗剂中毒的管理。
Emerg Med Clin North Am. 2007 May;25(2):309-31; abstract viii. doi: 10.1016/j.emc.2007.02.001.

引用本文的文献

1
Death due to unrecognized intoxication of nifedipine in an adult.一名成年人因未被识别的硝苯地平中毒死亡。
Forensic Toxicol. 2025 Jan;43(1):172-175. doi: 10.1007/s11419-024-00704-1. Epub 2024 Sep 23.
2
Nifedipine toxicity is exacerbated by acetyl l-carnitine but alleviated by low-dose ketamine in zebrafish in vivo.在斑马鱼体内,乙酰左旋肉碱会加剧硝苯地平毒性,但低剂量氯胺酮可减轻这种毒性。
J Appl Toxicol. 2020 Feb;40(2):257-269. doi: 10.1002/jat.3901. Epub 2019 Oct 9.
3
Management of Calcium Channel Blocker Toxicity in the Pediatric Patient.
小儿患者钙通道阻滞剂中毒的管理
J Pediatr Pharmacol Ther. 2019 Sep-Oct;24(5):378-389. doi: 10.5863/1551-6776-24.5.378.
4
Comprehensive review of cardiovascular toxicity of drugs and related agents.药物和相关制剂的心血管毒性的综合评价
Med Res Rev. 2018 Jul;38(4):1332-1403. doi: 10.1002/med.21476. Epub 2018 Jan 5.
5
Intralipid fat emulsion decreases respiratory failure in a rat model of parathion exposure.脂肪乳剂可降低对硫磷暴露大鼠模型中的呼吸衰竭发生率。
Acad Emerg Med. 2012 May;19(5):504-9. doi: 10.1111/j.1553-2712.2012.01337.x.
6
Combination of nifedipine and subtherapeutic dose of cyclosporin additively suppresses mononuclear cells activation of patients with rheumatoid arthritis and normal individuals via Ca(2+) -calcineurin-nuclear factor of activated T cells pathway.硝苯地平与环孢素亚治疗剂量联合通过 Ca(2+)-钙调神经磷酸酶-T 细胞激活因子途径抑制类风湿关节炎患者和正常人单核细胞的激活。
Clin Exp Immunol. 2012 Apr;168(1):78-86. doi: 10.1111/j.1365-2249.2012.04563.x.