Janković Slavenka, Raznatović Milena, Marinković Jelena, Maksimović Natasa, Janković Janko, Djikanović Bosiljka
Institute of Epidemiology, School of Medicine, University of Belgrade, Visegradska 26 11000 Belgrade, Serbia.
Acta Derm Venereol. 2009;89(4):364-8. doi: 10.2340/00015555-0669.
The aim of this study was to assess the role of stressful life events, lack of social support and attachment insecurity in triggering exacerbations of psoriasis. Outpatients experiencing exacerbation of psoriasis in the last 6 months (n = 110) were compared with outpatients affected by skin conditions in which psychosomatic factors are believed to play a minor role (n = 200). Stressful life events during the last 12 months were assessed with Paykel's Interview for Recent Life Events. Perceived social support and attachment relationship were assessed with the Multidimensional Scale of Perceived Social Support and Experiences in Close Relationships Scale, respectively. In comparison with controls the patients with psoriasis reported more stressful life events in the last year. The statistically significant difference was found only for the sum of the first 25 events (odds ratio (OR) 1.98; 95% confidence interval (CI) 1.37-2.87; p < 0.001). Also, patients with psoriasis were more likely to score higher on both anxiety (OR = 1.44; CI = 1.09-1.92; p = 0.011) and avoidance attachment scale (OR = 1.49; CI = 1.04-2.14; p = 0.030), and perceived less support from their social network than did the comparison subjects. The results of this study confirm the relevance of psychosocial factors in psoriasis.
本研究的目的是评估应激性生活事件、缺乏社会支持和依恋不安全感在引发银屑病病情加重中的作用。将过去6个月内银屑病病情加重的门诊患者（n = 110）与受心理社会因素被认为起次要作用的皮肤疾病影响的门诊患者（n = 200）进行比较。使用佩克尔近期生活事件访谈评估过去12个月内的应激性生活事件。分别使用领悟社会支持多维量表和亲密关系经历量表评估领悟社会支持和依恋关系。与对照组相比，银屑病患者报告在过去一年中有更多的应激性生活事件。仅在前25个事件的总和上发现了统计学上的显著差异（优势比（OR）1.98；95%置信区间（CI）1.37 - 2.87；p < 0.001）。此外，银屑病患者在焦虑（OR = 1.44；CI = 1.09 - 1.92；p = 0.011）和回避依恋量表（OR = 1.49；CI = 1.04 - 2.14；p = 0.030）上得分更高的可能性更大，并且与对照组相比，他们从社交网络中感受到的支持更少。本研究结果证实了心理社会因素在银屑病中的相关性。
