妊娠卵巢皮样囊肿中发生的鳞状细胞癌。

Squamous cell carcinoma arising in a dermoid cyst of the ovary in pregnancy.

机构信息

Department of Obstetrics and Gynaecology, Grosshadern, Ludwig-Maximilians-University of Munich 81377, Munich, Germany.

出版信息

Arch Gynecol Obstet. 2010 Mar;281(3):535-7. doi: 10.1007/s00404-009-1193-y. Epub 2009 Aug 18.

DOI:10.1007/s00404-009-1193-y

PMID:19688218

Abstract

BACKGROUND

A rare complication of mature cystic teratoma of the ovary is malignant transformation, mostly being squamous cell carcinoma (SCC). Due to small case series, there are no established standard surgical and postoperative procedures.

CASE

A 41-year-old pregnant woman presented with a right ovarian tumour. At 14 weeks of gestation, laparotomy with oophorectomy was performed. Histology revealed a pT1a poorly differentiated SCC with lymphovascular invasion. She delivered a healthy infant at 39 weeks of gestation. Nine weeks after delivery, she underwent complete surgical resection and was staged pT1a, pN0 (0/40) pMx, G0. No further treatment was given and 37 months later she is still free of disease.

CONCLUSION

For this rare entity complete surgical resection seems to be a safe treatment.

摘要

背景

卵巢成熟囊性畸胎瘤的一种罕见并发症是恶性转化，主要为鳞状细胞癌（SCC）。由于病例系列较少，因此没有既定的标准手术和术后程序。

病例

一名 41 岁孕妇出现右侧卵巢肿瘤。在妊娠 14 周时进行了剖腹手术和卵巢切除术。组织学显示为 pT1a 低分化 SCC 伴淋巴血管侵犯。她在 39 周妊娠时分娩了一个健康的婴儿。分娩后 9 周，她接受了完全手术切除，并分期为 pT1a、pN0（0/40）pMx、G0。未给予进一步治疗，37 个月后仍无疾病。