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In vivo inactivation of transglutaminase during the acute acrylamide toxic syndrome in the rat.

作者信息

Bergamini C M, Signorini M

机构信息

Institute of Biological Chemistry, University of Ferrara, Italy.

出版信息

Experientia. 1990 Mar 15;46(3):278-81. doi: 10.1007/BF01951765.

DOI:10.1007/BF01951765
PMID:1968852
Abstract

The activity of liver and brain transglutaminase is rapidly lost following i.p. injection of acrylamide (50-200 mg/kg). Other enzymes investigated were not modified by the treatment, with the exception of brain enolase.

摘要

相似文献

1
In vivo inactivation of transglutaminase during the acute acrylamide toxic syndrome in the rat.
Experientia. 1990 Mar 15;46(3):278-81. doi: 10.1007/BF01951765.
2
Sensitivity of transglutaminase in rat tissues to administration of acrylamide in vivo.大鼠组织中转谷氨酰胺酶对体内丙烯酰胺给药的敏感性。
Arch Toxicol. 1990;64(6):509-10. doi: 10.1007/BF01977637.
3
The etiology of acrylamide neuropathy: possible involvement of neuron specific enolase.丙烯酰胺神经病的病因:神经元特异性烯醇化酶可能参与其中。
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4
Inhibition of glyceraldehyde-3-phosphate dehydrogenase in tissues of the rat by acrylamide and related compounds.丙烯酰胺及相关化合物对大鼠组织中甘油醛-3-磷酸脱氢酶的抑制作用。
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The use of rat brain slices as an in vitro model for mechanistic evaluation of neurotoxicity-studies with acrylamide.使用大鼠脑片作为丙烯酰胺神经毒性机制评估的体外模型进行研究。
Neurotoxicology. 1991 Summer;12(2):225-34.
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The etiology of toxic peripheral neuropathies: in vitro effects of acrylamide and 2,5-hexanedione on brain enolase and other glycolytic enzymes.中毒性周围神经病的病因:丙烯酰胺和2,5 -己二酮对脑烯醇化酶及其他糖酵解酶的体外作用
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Neurotoxicity of acrylamide in developing rat brain: changes in the levels of brain biogenic amines and activities of monoamine oxidase and acetylcholine esterase.丙烯酰胺对发育中大鼠脑的神经毒性:脑内生物胺水平、单胺氧化酶及乙酰胆碱酯酶活性的变化
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Biochemical studies of acrylamide neuropathy.丙烯酰胺神经病变的生化研究。
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引用本文的文献

1
Transglutaminases: nature's biological glues.转谷氨酰胺酶:自然界的生物胶水。
Biochem J. 2002 Dec 1;368(Pt 2):377-96. doi: 10.1042/BJ20021234.
2
Sensitivity of transglutaminase in rat tissues to administration of acrylamide in vivo.大鼠组织中转谷氨酰胺酶对体内丙烯酰胺给药的敏感性。
Arch Toxicol. 1990;64(6):509-10. doi: 10.1007/BF01977637.

本文引用的文献

1
Protein measurement with the Folin phenol reagent.使用福林酚试剂进行蛋白质测定。
J Biol Chem. 1951 Nov;193(1):265-75.
2
THE ACYL-ENZYME INTERMEDIATE AND THE KINETIC MECHANISM OF THE GLYCERALDEHYDE 3-PHOSPHATE DEHYDROGENASE REACTION.甘油醛-3-磷酸脱氢酶反应的酰基-酶中间体及动力学机制
J Biol Chem. 1965 Feb;240:844-55.
3
The etiology of acrylamide neuropathy: possible involvement of neuron specific enolase.丙烯酰胺神经病的病因:神经元特异性烯醇化酶可能参与其中。
Brain Res. 1980 May 26;190(2):529-35. doi: 10.1016/0006-8993(80)90294-2.
4
Neurotoxicity of acrylamide and related compounds and their effects on male gonads in mice.丙烯酰胺及相关化合物的神经毒性及其对小鼠雄性性腺的影响。
Arch Toxicol. 1981 Jun;47(3):179-89. doi: 10.1007/BF00368678.
5
Inhibition of brain enolases by acrylamide and its related compounds in vitro, and the structure-activity relationship.丙烯酰胺及其相关化合物对脑烯醇化酶的体外抑制作用及其构效关系。
Experientia. 1984 Sep 15;40(9):971-2. doi: 10.1007/BF01946464.
6
The etiology of acrylamide neuropathy: enolase, phosphofructokinase, and glyceraldehyde-3-phosphate dehydrogenase activities in peripheral nerve, spinal cord, brain, and skeletal muscle of acrylamide-intoxicated cats.丙烯酰胺神经病变的病因:丙烯酰胺中毒猫的外周神经、脊髓、脑和骨骼肌中的烯醇化酶、磷酸果糖激酶及甘油醛-3-磷酸脱氢酶活性
Toxicol Appl Pharmacol. 1981 Sep 15;60(2):324-33. doi: 10.1016/0041-008x(91)90235-7.
7
Rabbit liver glycogen synthase. Purification and comparison of the properties of glucose-6-P-dependent and glucose-6-P-independent forms of the enzyme.兔肝糖原合酶。该酶依赖葡萄糖-6-磷酸和不依赖葡萄糖-6-磷酸形式的性质纯化及比较。
J Biol Chem. 1984 Mar 25;259(6):3429-34.
8
Early and dose-dependent decrease of retrograde axonal transport in acrylamide-intoxicated rats.丙烯酰胺中毒大鼠逆行轴突运输的早期和剂量依赖性降低
J Neurochem. 1983 Feb;40(2):447-54. doi: 10.1111/j.1471-4159.1983.tb11303.x.
9
Mechanism and basis for specificity of transglutaminase-catalyzed epsilon-(gamma-glutamyl) lysine bond formation.转谷氨酰胺酶催化形成ε-(γ-谷氨酰)赖氨酸键的机制及特异性基础。
Adv Enzymol Relat Areas Mol Biol. 1983;54:1-56. doi: 10.1002/9780470122990.ch1.
10
New amino acids derived from reactions of epsilon-amino groups in proteins with alpha, beta-unsaturated compounds.蛋白质中ε-氨基与α,β-不饱和化合物反应衍生出的新氨基酸。
Biochemistry. 1967 Dec;6(12):3766-70. doi: 10.1021/bi00864a021.